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Istituto Veneto di Scienze, Lettere ed Arti - Testata per la stampa

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Giampietro Schiavo

Giampietro Schiavo

Professore di Neurobiologia cellulare nell'University College of London

- s.s. eletto il 23 marzo 2019

Education and Qualifications
MSc in Biological Sciences, University of Padua, Italy (1992)
MSc in Chemistry and Pharmaceutical Technology, University of Padua, Italy (1988)
Employment History
2019-present Deputy Director, UCL Queen Square Institute of Neurology, UK 
2018-present Associate member, The Francis Crick Institute, UK 
2017-present UK Dementia Research Institute at UCL Professorship
2015-present Deputy Head, Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, UK
2014-present Lead Academic Scientist, ARUK UCL Drug Discovery Institute, UCL, UK
2013-present Professor of Cellular Neurobiology, UCL Queen Square Institute of Neurology, UCL, UK
Expected end of contract: 24.06.2027
2007-2013 Honorary Professor, Dept of Cell & Developmental Biology, UCL, UK
2003-2013 Senior Group Leader (tenured), Cancer Research UK London Research Institute, UK
2003-2006 Honorary Reader, Dept of Biochemistry and Molecular Biology, UCL, UK
1997-2003 Honorary Senior Research Fellow, Dept of Biochemistry and Molecular Biology, UCL, UK
1996-2002 Group Leader, Cancer Research UK London Research Institute, UK
1992-1995 Senior Researcher, Dept of Biomedical Sciences, University of Padua, Italy
1983-1991 Research Associate, Institute of General Pathology, University of Padua, Italy
PROFESSIONAL ACTIVITIES
Membership of Professional Bodies
2014-present Fellow, Royal Society of Biology (FRSB)
2011-present Fellow, Academy of Medical Sciences (FMedSci)
2010-present Member, European Molecular Biology Organization (EMBO)
Membership of Learned Societies
2015-present Member, British Society for Cell Biology
1994-present Member, International Society for Neurochemistry 
1997-2010 Member, Biochemical Society
1993-1997 Member, Italian Society of Biophysics and Molecular Biology (SIBBM)
Membership of Review/Grant Committees (from 2002)
2018-present Deputy Chair, MRC Neurosciences & Mental Health Board
2018 Neurodegeneration Challenge Network, Chan Zuckerberg Initiative (CZI)
2018 The Wellcome Trust "Cellular and Molecular Neuroscience" ERG Committee (co-opted)
2015-2018 MRC Neurosciences & Mental Health Board
2011-2014 The Wellcome Trust "Cellular and Molecular Neuroscience" ERG Committee
2012 French National Agency of Research (ANR) "Cell and Developmental Biology" Committee
2009-2010 Motor Neuron Disease Association Funding Committee
2005-2013 Panel of experts for the French National Agency of Research (ANR, Paris, France)
2005 Panel member for the evaluation of the RFA AI-04-018 cooperative agreements (U54): 
Centers of Excellence for Biodefense and Emerging Infectious Diseases", NIH NIAID
2004-2008 Wellcome Trust "Neuroscience and Mental Health" Funding Committee 
2004 Panel of experts for Research Council of Norway
2003-2007 Panel of experts for Association Francaise contre les Myopathies
2003 Panel member for the evaluation of the RFA AI-02-026 grants: "Cooperative Research 
for the Development of Vaccines, Adjuvants, Therapeutics, Immunotherapeutics, and 
Diagnostics for Biodefense", NIH NIAID 
2002-2010 Grant reviewer, United States of America-Israel Binational Science Foundation, USA
2002 Panel of experts for Telethon Italia
2002 Panel member for the evaluation of the RFA 02-002 grants "Rapid Response Grant
Program on Bioterrorism-related Research", NIH NIAID 
Editorial Boards
2016-present Editorial Board, Matters
2008-present Review Editor, Frontiers in Neuroengineering
2008-present Editorial Board, Protein Journal
2007-present Editor, Journal of Cell Science (Neuroscience)
2009-2016 Academic Editor, PLoS Biology
2002-2015 Editorial Board, Traffic
2009-2015 Editorial Board, Cell Death & Disease
2006-2009 Editorial Board, Neurotoxicity Research 
2005-2009 Deputy Chief Editor, Journal of Neurochemistry 
2002-2005 Editor, Journal of Neurochemistry
Advisory Boards/ Board of Directors
2019-present Scientific Advisory Board, IRCCS Istituto Neurologico Carlo Besta, Milan (I)
2019-present International Neurotoxin Association (INA), Past President
2017-2019 International Neurotoxin Association (INA), President 
2018 Scientific Advisory Board, "Synaptopathies Wellcome Collaborative Award"
2015-2018 Advisory Board, University of Milan (I).
2015-2017 International Neurotoxin Association (INA), President elect
2010-2017 International Neurotoxin Association (INA), Board of Directors
2013-2015 International Neurotoxin Association (INA), Treasurer
2007-2010 The Neurotoxin Institute Steering Committee, New York (NY)
2006-2013 Research Board of the Chemical Biology Centre, London (UK)
2005-2006 Advisory Board of the Chemical Biology Centre, London (UK)
Senior Mentorship
2016-present Barney Bryson, PhD; UCL Excellence Fellowship. UCL Institute of Neurology (UK)
2016-present Yongsoo Park, PhD; EMBO Young Investigator. Izmir International Biomedicine and Genome Institute (TR)
2016-present Alexander Rossor, PhD; Wellcome Trust Postdoctoral Training Fellow. UCL Institute of Neurology (UK)
2016-2017 Alessio Vagnoni, PhD; NC3R Fellow; Laboratory for Molecular Biology - UCL Institute of Neurology (UK). Transferred in 2017 to King's College London
2015-present Pietro Fratta, PhD; MRC Clinical Fellow. UCL Institute of Neurology (UK)
Award & Selection Committees
2017 Journal of Cell Science - Company of Biology Travelling Fellowship selection chair
2017 ETOX18 selection committee
2016 Institute of Neurology Queen Square Prize selection panel
2015 9th Basic and Therapeutic Aspects of Botulinum and Tetanus Toxins selection committee
2013 EMBO Meeting selection committee
2013 ETOX16 selection committee
2012 8th Basic and Therapeutic Aspects of Botulinum and Tetanus Toxins selection committee
2009-2011 Peter and Patricia Gruber International Research Award in Neuroscience committee
2010 Journal of Cell Science - Company of Biology Travelling Fellowship selection chair
Scientific Institute Evaluation/Recruitment Committees
2018 Institut Pasteur, Department of Cell Biology and Infection, Paris (F)
2018 MRC Cognition and Brain Sciences Unit, Cambridge (UK) (Chair)
2018 Centro de Biologia Molecular Severo Ochoa (CBMSO), Madrid (E)
2015-2017 Institut Pasteur Recruitment Committee, Paris (F)
2014-2016 Evaluation and Steering Committee, Butantan Institute, Sao Paulo (Br)
2015 Laboratory of Molecular Biology (Neuroscience Division), Cambridge (UK)
2014 Institut Curie recruitment committee, Paris (F)
2014 Maurice Wohl Institute recruitment committee, King's College London (UK)
2013 Department of Health Science (DISS), University of Milan (I)
2013 Promotion Committee, Max F. Perutz Laboratories, Vienna (AT)
2009 Institut Curie/Inserm Unit "Signalisation, neurobiologie et cancer", Paris (F)
2009 Institut Pasteur, Department of Cell Biology and Infection, Paris (F)
UCL Committees
2017-present Discoveries CTR Steering Committee
2017-present Discoveries CTR Seminar Programme
2017-present UCL-DRI Strategy group
2017-present UCL-DRI Steering group
2016-present ARUK Drug Discovery Institute UCL Steering Committee 
Industrial consultancies
2018 External advisor, Takeda Exploratory Challenge (TEC), Takeda (J)
2018 Takeda CNS Drug Discovery Unit (J)
2015-2018 Circ MedTech Ltd (Is) regarding the WHO programme of HIV prevention http://www.who.int/hiv/pub/malecircumcision/vmmc-progress-brief-2017/en/2016 Allergan UK
2015-2016 GSK-Butantan Institute (Sao Paolo, Br) Partnership Advisory board
2012-2015 Janus Development, Barcelona (E)
2006-2007 Scientific expert, High Court of Justice, London (UK)
AWARDS AND HONOURS 
Fellowships
2017 UK Dementia Research Institute at UCL Professorship 
2009 CaRiPaRo Foundation Visiting Professorship at the Scuola Galileiana di Studi Superiori, University of Padua (I)
1994 Long term European Molecular Biology Organization fellowship (Dr JE Rothman, Memorial Sloan-Kettering Cancer Center, New York (NY)
Awards
2002 Giovanni Armenise-Harvard Foundation Career Development Award
1995 International Society for Neurochemistry (ISN) Young Scientist Award
1993 Award of the Italian National Academy of Sciences "Dott Giuseppe Borgia"
1988 Award for the best student of Chemistry and Pharmaceutical Technology, University of Padua (I)
PRESENTATIONS
Invited Lectures (from 2014)
2019 Toxins2019 - 11th Basic and Therapeutic Aspects of Botulinum and Other Neurotoxins, Copenhagen (DK)
2018 29th International Symposium on ALS/MND, Glasgow (UK)
2018 90th Meeting of the Chilean Biological Society, Puerto Varas (CL) 
2018 Italian Institute of Technology Retreat, Pieve a Salti (I) (Keynote Lecture)
2018 2nd Nova Medical School Symposium on Chronic Diseases and Translational Science, Lisbon (P) (Keynote Lecture)
2018 CAJAL Advanced Neuroscience Training Program "Advanced imaging methods for cellular neuroscience", Bordeaux (F) (Keynote Lecture)
2018 "Synaptopathies", UCL Institute of Neurology, London (UK)
2018 20th Spinal Research Network meeting, London (UK)
2018 Asian and Oceanian Myology Centre/Malaysian Society of Neuroscience (AOMC/MSN). Kuala Lumpur (MY) (Plenary Lecture and Symposium presentation)
2018 Protein toxins: a journey between physiology and medicine, Padova (I) (Chair and Co-organiser)
2018 EMBO Workshop on: "Exocytosis and endocytosis: From synaptic vesicles to nanodiscs", Tenerife (ES)
2017 2nd Royal Netherlands Academy meeting "Cell Biology of the Axon: Progress Made and Promises Ahead", Amsterdam (NL)
2017 18th European Workshop on Bacterial Protein Toxins (ETOX18), Paris (F) (Chair and Co-organiser)
2017 International Microbiology & Biotechnology Conference, Busan (KR) (Plenary Speaker)
2017 Thierry Latran Foundation Grantees meeting, Ljubljana (SL)
2017 "Meeting the challenges of modelling neurodegenerative disease in mice" Royal Society Hooke Research Conference, (UK) (Chair and Co-organiser)
2017 "Neurotrophic factors" Gordon Research Conference, Newport (RI)
2017 IUBMB Focused Meeting on Emerging Concepts of the Neuronal Cytoskeleton, Puerto Varas (CL)
2017 12th Göttingen Meeting of the German Neuroscience Society, Göttingen (D)
2017 Toxins2017 - 10th Basic and Therapeutic Aspects of Botulinum and Other Neurotoxins, Madrid (E) (Plenary Speaker)
2016 Botulinum toxin in chronic pain syndromes, Royal Society of Medicine Pain Section, London (UK)
2016 6th International Charcot-Marie-Tooth and Related Neuropathy Consortium, Venice (I) (Plenary Speaker)
2016 Thierry Latran Foundation Grantees meeting, Milan (I)
2016 Keystone Symposia "Axons: From Cell Biology to Pathology", Santa Fe (NM) (Chair and Co-organiser)
2015 IST 18th World Congress on Animal, Plant and Microbial Toxins, Oxford (UK)
2015 Ipsen's annual Global Project Review, Oxford (UK) (plenary lecture)
2015 5th British Neurotoxin Network annual meeting, Oxford (UK) (plenary lecture)
2015 ClosPath, Freiburg (D) (Special plenary lecture)
2015 "Infections of the Nervous System" Gordon Research Conference, Hong Kong (HK) (Scientific Committee)
2015 Consiglio Nazionale delle Ricerche, Neuroscience Annual Retreat, Pisa (I) (Plenary Speaker)
2015 17th European Workshop on Bacterial Protein Toxins (ETOX17), Braga (P) (Chair and Co-organiser)
2015 "Signalling from Basal Membranes" Minisymposium, Cologne (D)
2015 9th German Parkinson's Disease Congress, Berlin (D)
2015 Alzheimer's Research UK Conference 2015, London (UK) (Organiser)
2015 9th Basic and Therapeutic Aspects of Botulinum and Tetanus Toxins, Lisbon (P) (Chair and Co-organiser)
2014 XVI Annual Scientific Meeting of Butantan Institute, Sao Paulo (Br)
2014 Bioeconomy Rome 2014: Therapeutic Frontiers for Neurodegenerative Diseases, Rome (I)
2014 EMBO Workshop "Current Advances in Membrane Trafficking: Implications for Cell Polarity and Disease", Punta Arenas (CL)
2014 FENS Forum 2014, Milan (I) (Chairman)
2014 "Intracellular transport", Münster (D) (Plenary Lecture)
2014 CMIAD retreat, University of Sheffield (UK) (Plenary Lecture)
Invited Seminars (from 2014)
2019 Humanitas University, Milan (I). Host: Prof. M. Matteoli
2018 Abbvie, Ludwigshafen (D). Host: Dr L Gasparini
2018 University of Cambridge, Cambridge (UK). Host: Prof M Coleman
2018 King's College London, London (UK). Host: Dr O Marin
2018 Takeda, Shonan (J). Host: Dr C Davies
2017 UCL Institute of Neurology Inaugural Lecture, London (UK). Host: Prof M Hanna
2017 Dept of Physiology, Anatomy and Genetics, University of Oxford (UK). Host: Prof Z Molnar
2017 Lilly UK, Windlesham (UK). Host: Dr M Sher
2016 Centre for Neuroregeneration, University of Edinburgh (UK). Host: Prof P Brophy
2016 San Raffaele Telethon Institute for Gene Therapy, Milan (I). Host: Dr A Gritti
2015 MRC Centre of Neuromuscular Diseases, UCL (UK). Host: Prof M Hanna
2015 Imperial College London (UK). Host: Prof S di Giovanni
2015 University of Leeds (UK). Host: Prof V Ponnambalam 
2015 Laboratory of Molecular Biology (LMB) Cambridge (UK). Host: Dr S Bullock
2015 Wolfson Institute for Biomedical Research, UCL. Host: Prof W Richardson
2014 Pontificia Universidad Católica de Chile, Santiago (CL) Host: Prof F Bronfman
2014 Brain Research Institute, ETH, Zurich (CH) Host: Prof M Schwab
2014 Institut Pasteur, Paris (F) Host: Dr JC Olivo-Marin
2014 DZNE, Bonn (D) Host: Dr F Bradke
2014 DIBIT San Raffaele Scientific Institute, Milan (I) Host: Dr A Bolino
GRANTS (from 2014)
I successfully obtained three CRUK core grants, which supported my research programme from the creation of my laboratory at the CRUK LRI in 1997. This programme has been renewed in 2012 but ended in 2014 due to my move to UCL-Institute of Neurology
2018 Fondazione Cassa di Risparmio Padova e Rovigo Visiting Programme. University of Padova (I) PI: M Pirazzini and UCL Institute of Neurology (UK) PI: G Schiavo. €33,500
2018 Rosetree Foundation. Gene therapy for Charcot-Marie-Tooth disease. To: J Sleigh and G. Schiavo. £12,995
2018 Consiglio Nazionale delle Ricerche (I). Joint Intl bilateral laboratory in Biomedical Sciences: CNR Pisa (I) PI: M Caleo and UCL Institute of Neurology (UK) PI: G Schiavo. €148,000
2018 The Wolfson Foundation. Genetic therapy preclinical facility. £2M
2018 Lilly Research Awards program. Mechanism of pathological tau release from rodent and human AD synapses. To: G Schiavo. $264,999.00 for two years.
2017 UK DRI Foundation grant. Restoring axonal transport deficits as a therapeutic strategy for neurodegenerative diseases. To: G Schiavo. £0.6M for five years
2017 MRC Dementia Research Institute. CoI. With A Thompson and other 25 co-applicants. £250M
2016 Horizon2020 EU Research and Innovation Programme. "Discoveries Centre for Regenerative and Precision Medicine". UCL and five Portuguese Universities coordinated by the University of Minho (with J Knowles, I Wall, A Schätzlein, V Mudera, R Day, T McHugh and J Kinghorn). €15M of which €5.1M at UCL
2016 UCL Excellence Fellowship. Restoring Lost Motor Function. To: JB Bryson.
2016 The Royal Society Newton International Fellowship. Neurotrophins and the balance between retrograde signalling and autophagic flux in the axon. To: O Marcelo Lazo. £99,000 for 24 months
2016 Becas-Chile. Neurotrophins and the balance between retrograde signalling and autophagic flux in the axon. Subsistence support to O Marcelo Lazo. £46,000 for 24 months
2016 MRC Programme Grant. Novel and bespoke mouse models for dissecting neurodegenerative disease. MR/N501931/1. To: EL Fisher, L Greensmith, G Schiavo, A Isaacs, P Fratta, F Wiseman and A Acevedo. £1.78M for four years
2016 Horserace Betting Levy Board. Why do horses roar? From the beginning to the end of recurrent laryngeal neuropathy. To: R Piercy, A. Draper, J. Cheetham, G Schiavo, S Brown and J Perkins. £97,867 for 24 months
2016 NC3Rs Fellowship. A new Drosophila-based strategy to study mitochondrial transport and neuronal ageing in vivo. To: A Vagnoni. £195,000 for 36 months
2016 The Wellcome Trust Postdoctoral Training Fellowship for Clinicians "Control of receptor trafficking as a therapeutic target in the inherited neuropathies" 110043/Z/15/Z. To: A Rossor and G Schiavo. £412,604 for 36 months
2016 MNDA PhD Fellowship. Regulation of intracellular traffic by TBK1 and its relevance to Amyotrophic Lateral Sclerosis. To: G Schiavo and P Fratta. £92,842 for three years
2015 MRC Clinical Fellowship. Investigating deficits of axonal RNA metabolism and axonal signalling in ALS. To P. Fratta. £1,156,170 for four years
2015 Fondation Thierry Latran. Deficits in axonal transport as a target for pharmacological intervention in Amyotrophic Lateral Sclerosis. To: G Schiavo and L Greensmith. €117,000 for 18 months
2015 The Wellcome Trust Senior Investigator Award. The mechanism controlling sorting and axonal retrograde transport in neurons. £1.75M for five years
2014 Alzheimer's Research UK - UCL Drug Discovery Institute. Lead Academic Scientist (with B. De Strooper and J. Hardy). £10M for 5 years
2014 Medical Research Council's UK Dementias Platform (UKDP). Co-PI (UCL Chairman: T.T. Warner). £1.9M for the set-up of a new high-throughput phenotypic cell screening facility
2014 BBSRC Industrial CASE PhD Fellowship. Mechanisms controlling the axonal retrograde transport pathway. To: G Schiavo and L Greensmith. £92,694 for 48 months
2014 Sir Henry Wellcome Fellowship (to Dr J Sleigh). The Welcome Trust. Dissecting Neuronal Specificity in Hereditary Neuropathy. £250,000 for 48 months
TEACHING AND MENTORING
Graduate Student supervisor. Cancer Research UK, London Research Institute
Shona L. Osborne (48 months; PhD thesis defended 07/2001)
Giovanna Lalli (48 months; PhD thesis defended 02/2002) 
Gerald Hammond (48 months; PhD thesis defended 11/2005)
Katrin Deinhardt (48 months; PhD thesis defended 11/2005)
Stephanie Bohnert (48 months; PhD thesis defended 07/2006)
Fabrizia Cesca (48 months; PhD thesis defended 09/2007)
Guillermo Menendez (48 months; PhD thesis defended 10/2010)
Marco Terenzio (48 months; PhD thesis defended 11/2010)
Anna Wade (51 months; PhD thesis defended 02/2011); awarded 3-month extension by the Wellcome Trust
Arisa Yabe (48 months; PhD thesis defended 12/2011)
Martin Wallace (48 months; PhD thesis defended 11/2014)
Kinga Bercsenyi (51 months; PhD thesis defended 02/2015); awarded 3-month extension for maternity leave
Nathalie Bradley-Schmieg (51 months; PhD thesis defended 03/2016); awarded 3-month extension for maternity leave
Graduate Student supervisor. UCL-Institute of Neurology
Katherine Gibbs (48 months; PhD thesis defended 09/2015)
Alexander Fellow (51 months; PhD thesis defended 03/2019); awarded 3-month extension by the Leonard Wolfson PhD Programme
Marta Budzinska (started 10/2014)
Ione Meyer (started 09/2015)
Matthew Bentham (started 09/2016)
David Villaroel (started 10/2016)
Samantha De La-Roche (started 10/2017)
Ellie Rhymes (started 10/2017)
Graduate Student supervisor. UCL/NIMH (USA)
Jose Norberto Vargas (started 09/2015)
Graduate Student supervisor (secondary)
Jorg D Hoeck, Cancer Research UK London Research Institute (48 months; PhD thesis completed)
Xenia Snetkov, Cancer Research UK London Research Institute (48 months; PhD thesis completed)
Alex J Clark, UCL Institute of Neurology (PhD thesis completed)
Emily May Burns, Cancer Research UK London Research Institute (48 months; PhD thesis completed)
Aarti Hitendra Ruparelia, Institute of Neurology (PhD thesis completed)
Oscar Morice, UCL Institute of Neurology (UK) (PhD thesis completed)
Anna Hands, UCL Institute of Neurology (UK)
Graduate Rotation Student
David Lynch (Oct 2013-Jan 2014) Leonard Wolfson PhD Programme
Albert Snowball (Jan 2014-May 2014 Wellcome Neuroscience Programme
Melissa Wren (Oct 2014-Jan 2015) Leonard Wolfson PhD Programme
Ione Meyer (Oct 2014-Jan 2015) MRC Neuromuscular Disease PhD Programme
Alexander Fellow (Feb 2015-May 2015) Leonard Wolfson PhD Programme
Matthew Bentham (Oct 2015-Jan 2015) Leonard Wolfson PhD Programme
Grace O'Regan (Nov 2015-Jan 2016) 4 year PhD Programme in Clinical Neurosciences
Martha McLaughlin (Nov 2016-Jan 2017) 4 year PhD Programme in Clinical Neurosciences
Liam Kempthorne (Nov 2017-Jan 2018) Leonard Wolfson PhD Programme
Graduate Student External supervisor
2007-2011 Eugenio Fornasiero Supervisor: Prof F Valtorta, Istituto Scientifico San Raffaele, Milan (I)
2003-2006 Rosanna Piccirillo Supervisor: Dr MV Schiaffino Istituto Scientifico San Raffaele, Milan (I)
2002-2005 Dario Bonanomi Supervisor: Prof F Valtorta, Istituto Scientifico San Raffaele, Milan (I)
1999-2002 Barbara Borgonovo Supervisor: Prof J Meldolesi, Istituto Scientifico San Raffaele, Milan (I)
2014-2017 Mea Holm Supervisor: Prof M Schwab, University of Zürich (CH)
2016-present Valentina Morra Supervisor: Prof A De Matteis, TIGEM (I)
2017-present Amadeus Xu Supervisor: Dr M Way, The Francis Crick Institute, London (UK)
2018-present Antonio Masone Supervisor: Prof R Chiesa, Mario Negri Institut, Milan (I)
2018-present Francesca Houghton Supervisor: Dr N McDonald, The Francis Crick Institute, London (UK)
2018-present Antonie Martiniuc (MRes) Supervisor: S Ultanir, The Francis Crick Institute, London (UK)
2019-present Alessandra Pisciottani Supervisor Prof G Consalez, Istituto Scientifico San Raffaele, Milan (I)
Mentoring 
2014-present Mentor: Sao Bettencourt. Athena Swan UCL Institute of Neurology Mentoring Programme
2017-2018 Mentor: Nathalie Welsh. Athena Swan UCL Institute of Neurology Mentoring Programme
2017-2018 Personal tutor: Laura MacGregor MSc Neuromuscular Diseases student
2017-2018 Personal tutor: Meenakshi Siddharthan MSc Neuromuscular Diseases student
2014-2016 Mentor: Kirsi Kinnunen. Athena Swan UCL Institute of Neurology Mentoring Programme
Graduate Student course teacher
2019 Master Peripheral Nervous System disorders, University of Milan (I)
2018 Cajal Advanced Neuroscience Training Program "Advanced imaging methods for cellular neuroscience", Bordeaux (F) (Keynote Lecture)
2018 Peripheral Nervous System disorders. DIBIT, Istituto Scientifico San Raffaele, Milan (I)
2016 International School "Lipid-protein interactions and organelle function", Spetses (GR)
2016 7th HKU-Pasteur Cell Biology Course, Honk Kong University, Hong Kong (HK)
2014 Pontificia Universidad Católica de Chile, Santiago (CL)
2014 FENS School "Synapse dynamics in circuit formation, learning and disease", Milan (I)
2002-present Cell Biology Course, Institute Pasteur, Paris (F)
2009 PhD Corse on "Neuroregeneration'. DIBIT, Istituto Scientifico San Raffaele, Milan (I)
2008 Cell Biology and Neurobiology PhD program, Karolinska Institute, Stockholm (S)
1999-2008 Laboratory of Molecular Cell Biology (LMCB), University College London (UK)
2005 International School for Advanced Studies (SISSA/ISAS), Trieste (I)
2002 Membrane Trafficking Course, Institute Gulbenkian, Oeiras (P)
1998 International School "Molecular mechanisms of transcellular signalling", Spetses (GR)
1995 FEBS Advanced Course "Molecular Dynamics of Biomembranes", Cargese (F)
1993 General Pathology, University of Padua (I)
Postdoctoral Courses 
2016 Interview Skills, University College London (UK)
PhD upgrades 
2019 Claudia Cannavo, UCL Queen Square Institute of Neurology (UK)
2018 Alan Mejia Maza, UCL Institute of Neurology (UK)
2017 Luke Hill, UCL Institute of Neurology (UK)
2016 Justin Tosh, UCL Institute of Neurology (UK)
2016 Claire Wu, UCL Institute of Neurology (UK)
PhD Examinations
2019 Luis Valois, University of Bristol (UK) and Ipsen (UK)
2019 Amanda Almacellas Barbanoj, Istituto Italiano di Tecnologia (I)
2019 Cristina Mantovani, Humanitas University (I)
2018 Jacquie Maignell, Sorbonne Universite (F) and Ipsen (UK)
2018 Annalisa Cavallini, UCL Institute of Neurology (UK) and Eli Lilly (UK)
2018 Hamish Crerar, Laboratory for Cell and Molecular Biology, UCL, London (UK)
2017 Roman Praschberger, UCL Institute of Neurology (UK)
2017 Mea Holm, University of Zürich (CH) 
2016 Ha Thi Hoang, University of Cambridge (UK)
2016 Azzura Margiotta, Universita' della Tuscia, Viterbo (I)
2016 Giacomo Frati, San Raffaele Telethon Institute for Gene Therapy, Milan (I)
2016 Nathalie Higgs, University College London (UK)
2015 Teresa De Nadai, Scuola Normale Superiore, Pisa (I)
2015 Masue Marbiah, University College London (UK)
2013 Iain Harris, University of Bath (UK)
2012 Levent Kaya, University of Innsbruck (AT) 
2012 Kimberley Boney, University of Glasgow (UK)
2012 Naila Ben Fredj, King's College London (UK)
2012 Katrijn Coen, VIB Center for the Biology of Disease, KU Leuven (B)
2011 Claudio Raimondi, Blizard Institute of Cell and Molecular Science, QMLU, London (UK)
2011 Andrew Porter, Laboratory for Cell and Molecular Biology, UCL, London (UK)
2010 Elisabetta Babetto, The Babraham Institute, Cambridge (UK)
2010 Daniel Henaff, Universite Montpellier II, Montpellier (F)
2010 Louise Kay, King's College London (UK)
2009 Sigrid S Skanland, Norwegian Radium Hospital, University of Oslo, Oslo (N)
2008 Tom Kershaw, Laboratory for Cell and Molecular Biology UCL, London (UK)
2008 Karen Houston, Medical Research Council, National Institute for Medical Research (UK)
2006 Athanasios Konstantakopoulos, Wellcome Trust Biocentre, University of Dundee (UK)
2006 Kevin D'Arcy, Laboratory for Cell and Molecular Biology UCL, London (UK)
2006 Francesca Orsini, European Institute of Oncology, Milan (I)


PATENTS
Schiavo G, Rothman JE and Söllner TH. Methods and compositions for modulating vesicle release. WO Patent 1,997,021,729, 1997
Iglesias T and Schiavo G. Kinase D interacting protein. WO Patent App. PCT/GB2001/003,977, 2001
Caccin P, De Grandis D, Montecucco C, Ravenni R, Rigoni M, Rossetto O and Schiavo G. Products for topical application comprising lysophospholipids and fatty acids. EP05015645.4; 19/07/2005. US 2007/0036737; 15/02/2007.
Commercial products
Several antibodies characterised in the laboratory are now distributed by Cancer Research Technology to different commercial entities. Among these, the monoclonal antibody 2C11 directed against PtdIns(4,5)P2 is marketed by Echelon (http://echelon-inc.buyol.com/echelon-inc/ERL%20Webpage/index.htm) and Molecular Probes (http://www.probes.com/); the monoclonal 1F8/3 against rat Kidins220/ARMS by Abcam (www.abcam.com), GeneTex (http://www.genetex.com) and Novus Biologicals (http://www.novus-biologicals.com) and the monoclonal 6C6 against human spastin by Chemicon (http://www.chemicon.com)
PUBLICATIONS
To date I have published 164 research papers and 99 reviews in prestigious scientific journals, which have been highly cited (>22,000 total citations, >1,000 citations per year in 2011-2018; e.g. Schiavo et al. (1992) Nature 359:832, 1,705 citations; Schiavo et al. (2000) Physiol Rev 80:717, 1,264 citations; Hafezparast et al. (2003) Science 300:808, 711 citations). 
My h-index is 78 and i10-index 200 (42 and 130 since 2014; source: Google Scholar).
Manuscripts preprints
Humphrey J, Birsa N, Milioto C, Robaldo D, Bentham M, Jarvis S, Bodo C, Garone MG, Devoy A, Rosa A, Bozzoni I, Fisher EMC, Ruepp M-C, Isaacs A, Schiavo G, Plagnol V and Fratta P (2019) FUS ALS-causative mutations impact FUS autoregulation and the processing of RNA-binding proteins through intron retention. bioRxiv. doi: https://doi.org/10.1101/567735Kanemitsu-Fujita A, Morishita S, Kjaer S, Fukuda M, Schiavo G and Nakamura T (2018) Comparable affinity of RabGDIα to GTP- and GDP-bound forms of Rab7 supports a four-state transition model for Rab7 subcellular localization. bioRxiv. doi: http://dx.doi.org/10.1101/287516.Sleigh JN, Tosolini JP, Gordon D, Devoy A, FrattaP, Fisher EMC, Talbot K and Schiavo G (2018) ALS mice carrying pathological mutant TDP-43, but not mutant FUS, display axonal transport defects in vivo. bioRxiv. doi: https://doi.org/10.1101/438812
Research Papers
1. Kalinski AL, Kar AN, Craver J, Tosolini AP, Sleigh JN, Lee SJ, Hawthorne A, Brito-Vargas P, Miller-Randolph S, Passino R, Shi L, Wong VSC, Picci C, Smith DS, Bassell GJ, Willis DE, Havton LA, Schiavo G, Giger RJ, Langley B and Twiss JL (2019) Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition. J Cell Biol, in press.
2. Sleigh JN, Tosolini AP and Schiavo G (2019) In vivo imaging of anterograde and retrograde axonal transport in rodent peripheral nerves. Methods Mol Biol, in press.
3. Vargas JNS, Wang C, Bunker E, Hao L, Maric D, Schiavo G, Randow F and Youle RJ (2019) Spatiotemporal control of ULK1 activation 1 by NDP52 and TBK1 during selective autophagy. Mol Cell, 74, 1-16
4. Goto-Silva L, McShane MP, Salinas S, Kalaidzidis Y, Schiavo G and Zerial M (2019) Retrograde transport of Akt by a neuronal Rab5-APPL1 signaling endosome. Sci Rep 9, 2433.
5. Shorrock HK, van der Hoorn D, Boyd PJ, Hurtado ML, Lamont DJ, Wirth B, Sleigh JN, Schiavo G, Wishart TM, Groen EJN and Gillingwater TH (2018) UBA1/GARS-dependent pathways drive sensory-motor connectivity defects in spinal muscular atrophy. Brain 141, 2878-94.
6. Clark AJ, Menendez G, AlQatari M, Patel N, Årstad E, Schiavo G and Koltzenburg M (2018) Functional imaging in microfluidic chambers reveal sensory neuron sensitivity is differentially regulated between neuronal regions. Pain 159, 1413-25.
7. Gibbs KL, Kalmar B, Rhymes ER, Fellows AD, Ahmed M, Whiting P, Davies C, Greensmith L and Schiavo G (2018) Inhibiting p38 MAPK alpha rescues axonal retrograde transport defects in a mouse model of ALS. Cell Death Dis 9, 596.
8. Tyzack GE, Hall C, Sibley C, Cymes T, Forostyak S, Meyer IFG, Schiavo G, Zhang S-C, Gibbons G, Newcombe J, Patani R and Lakatos A (2017) A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models. Nat Commun 8, 1164.
9. Sleigh JN, Gomez-Martin A, Wei N, Yang XL and Schiavo G (2017) Neuropilin 1 sequestration by neuropathogenic mutant glycyl-tRNA synthetase is permissive to vascular homeostasis. Sci Rep 7, 9216.
10. Kalmar B, Innes A, Wanisch K, Kolaszynska AK, Amelie Pandraud A, Kelly G, Abramov A, Reilly M, Schiavo G and Greensmith L (2017) Mitochondrial dysfunction leading to axonal transport deficits in mutant Hsp27 induced Charcot Marie Tooth Disease. Hum Mol Genet. 26, 3313-3326.
11. Sleigh JN, Dawes JM, West SJ, Wei N, Spaulding EL, Gómez-Martín A, Burgess RW, Cader MZ, Talbot K, Yang XL, Bennett DL and Schiavo G (2017) Sensory neuron fate is developmentally perturbed by Gars mutations causing human neuropathy. Proc Natl Acad Sci USA 114, E3324-E3333.
See: https://f1000.com/prime/727458357?ref=ypphttp://cmt.org.uk/new-therapeutic-targets-identified-in-charcot-marie-tooth-disease/http://www.musculardystrophyuk.org/news/news/new-study-unveils-developmental-aspect-to-cmt/?utm_sour...12. Richter S, Helm C, Meunier FA, Hering L, Campbell LI, Drukewitz SH, Undheim EAB, Jenner RA, Schiavo G and Bleidorn C (2017) Comparative analyses of glycerotoxin expression unveil a novel structural organization of the bloodworm venom system. BMC Evol Biol 17, 64.
13. Charlier CM, Debaisieux S, Foret C, Thouard A, Schiavo G, Gonzalez-Dunia D and Malnou CE (2016) Neuronal retrograde transport of Borna disease virus occurs in signaling endosomes. J Gen Virol. 97, 3215-3224.
14. Zussy C, Loustalot F, Junyent F, Gardoni F, Bories C, Desarmenien MG, Valero J, Bernex F, Henaff D, Bayo-Puxan N, Chen J-W, Lonjon N, De Koninck Y, Malva J, Bergelson JMB, Di Luca M, Schiavo G, Salinas S and Kremer EJ (2016) Coxsackievirus adenovirus receptor loss impairs adult neurogenesis, synapse content and hippocampus plasticity. J Neurosci 36, 9558-71.
15. Sleigh JN and Schiavo G (2016) Older but not slower: aging does not alter axonal transport dynamics of signalling endosomes in vivo. Matters 10.19185/matters.201605000018.
16. Twelvetrees AE, Pernigo S, Sanger A, Schiavo G, Steiner RA, Dodding MP, Holzbaur EL (2016) The dynamic localization of cytoplasmic dynein in neurons is driven by kinesin-1. Neuron 90, 1000-15.
17. Ahmed M, Machado P, Miller A, Spicer C, Herbelin L, He J, Noel J, Wang Y, McVey AL, Pasnoor M, Gallagher P, Statland J, Lu C-H, Kalmar B, Brady S, Sethi H, Samandouras G, Parton M, Holton JL, Weston A, Collinson L, Taylor JP, Schiavo G, Hanna MG, Barohn RJ, Dimachkie MM, Greensmith L (2016) Targeting protein homeostasis in sporadic inclusion body myositis. Sci Transl Med 8, 331ra41.
18. Sleigh JN, Weir GA and Schiavo G (2016) A simple, step-by-step dissection protocol for the rapid isolation of mouse dorsal root ganglia. BMC Res Notes 9, 82.
19. Debaisieux S, Encheva V, Chakravarty P, Snijders AP and Schiavo G (2016) Analysis of signaling endosome composition and dynamics using SILAC in embryonic stem cell-derived motor neurons. Mol Cell Proteomics 15, 542-57.
20. Gibbs K, Kalmar B, Sleigh JN, Greensmith L and Schiavo G (2016) In vivo imaging of axonal transport in murine motor and sensory neurons. J Neurosci Meth 257, 26-33.
21. Simão D, Pinto C, Fernandes P, Peddie CJ, Piersanti C, Collinson LM, Salinas S, Saggio I, Schiavo G, Kremer EJ, Brito C and Alves PM (2016) Evaluation of helper-dependent 1 canine adenovirus vectors in a 3D human CNS model. Gene Ther 23, 86-94.
22. Yasuda S, Morishita S, Fujita A, Nanao T, Wada N, Waguri S, Schiavo G, Fukuda M and Nakamura T (2016) Mon1-Ccz1 activates Rab7 only on the late endosome and dissociates from the lysosome in mammalian cells. J Cell Sci 29, 329-40. 
23. Schmieg N, Thomas C, Yabe A, Lynch DS, Iglesias T, Chakravarty P and Schiavo G (2015) Novel Kidins220/ARMS splice isoforms: potential specific regulators of neuronal and cardiovascular development. PLoS One 10, e0129944.
24. Simão D, Pinto C, Piersanti S, Weston A, Peddie CJ, Bastos AE, Licursi V, Schwarz SC, Collinson LM, Salinas S, Serra M, Teixeira AP, Saggio I, Lima PA, Kremer EJ, Schiavo G, Brito C and Alves PM (2014) Modeling human neural functionality in vitro: 3D culture for dopaminergic differentiation. Tissue Eng Part A 21, 654-68.
25. Bercsenyi K, Schmieg N, Bryson JB, Wallace M, Caccin P, Golding M, Zanotti G, Greensmith L, Nischt R and Schiavo G (2014) Nidogens are therapeutic targets for the prevention of tetanus. Science 346, 1118-23.
See: http://f1000.com/prime/725249770 http://www.ucl.ac.uk/news/news-articles/1114/281114-secrets-of-tetanus-toxicity http://www.medicalnewstoday.com/articles/286140.php http://healthmedicinet.com/secret-of-tetanus-toxicity-offers-new-way-to-treat-motor-neuron-disease/ https://hereditaryspasticparaplegia.wordpress.com/26. Wang Y, Chakravarty P, Ranes M, Kelly GP, Brooks PJ, Neilan E, Stewart A, Schiavo G and Svejstrup JQ (2014) Dysregulation of gene expression as the cause of Cockayne syndrome neurologic disease. Proc Natl Acad Sci U S A 111, 14454-9.
27. Terenzio M, Golding M, Russell MRG, Wicher K, Rosewell I, Spencer-Dene B, Ish-Horowicz D and Schiavo G (2014) Bicaudal-D1 regulates the intracellular sorting and signalling of neurotrophin receptors. EMBO J 33, 1582-98. 
28. Terenzio M, Golding M and Schiavo G (2014) siRNA screen of ES cell-derived motor neurons identifies novel regulators of tetanus toxin and neurotrophin receptor trafficking. Frontiers Cell Neurobiol 8, 140.
29. Hislop JN, Islam TA, Eleftheriadou I, Carpentier DCJ, Trabalza A, Parkinson M, Schiavo G and Mazarakis ND (2014) Rabies virus envelope glycoprotein targets lentiviral vectors to the axonal retrograde pathway in motor neurons. J Biol Chem 289, 16148-63.
30. Garrett CA, Barri M, Kuta A, Soura V, Deng W, Fisher EMC, Schiavo G and Hafezparast M (2014) DYNC1H1 mutation alters transport kinetics and ERK1/2-cFos signalling in a mouse model of distal spinal muscular atrophy. Brain 137, 1883-93.
31. Salinas S, Zussy C, Loustalot F, Henaff D, Menendez G, Morton PE, Parsons M, Schiavo G and Kremer EJ (2014) Disruption of the coxsackievirus and adenovirus receptor-homodimeric interaction triggers lipid microdomain- and dynamin-dependent endocytosis and lysosomal targeting J Biol Chem 289, 680-95.
32. Ferrari E, Gu C, Niranjan D, Restani L, Rasetti-Escargueil C, ObaraI I, Geranton SM, Arsenault J, Goetze TA, Harper CB, Nguyen TH, Maywood E, O'Brien J, Schiavo G, Wheeler DW, Meunier F, Hastings M, Edwardson JM, Sesardic D, Caleo M, Hunt SP and Davletov BA (2013) A synthetic self-assembling clostridial chimera for modulation of sensory functions. Bioconjug Chem 24, 1750-9.
33. Goold R, McKinnon C, Rabbanian S, Collinge J, Schiavo G and Tabrizi SJ (2013) Trafficking and degradation kinetics of newly formed PrPSc in the first minutes following initial prion conversion. J Cell Sci 126,3552-62.
34. Cogli C, Progida C, Thomas CL, Spencer-Dene B, Donno C, Schiavo G and Bucci C (2013) Charcot-Marie-Tooth type 2B disease-causing RAB7A mutant proteins show altered interaction with the neuronal intermediate filament peripherin. Acta Neuropathol 125, 257-72.
35. Restani L, Giribaldi F, Manich M, Bercsenyi K, Menendez G, Rossetto O, Caleo M and Schiavo G (2012) Botulinum neurotoxins A and E undergo retrograde axonal transport in primary motor neurons. PLoS Pathog 8, e1003087.
36. Rishal I, Kam N, Shinder V, Fisher EMC, Schiavo G and Fainzilber M (2012) Motor driven intracellular length sensing in neurons. Cell Rep 1, 1-9.
37. Scholz-Starke J, Cesca F, Schiavo G, Benfenati F and Baldelli P (2012) Kidins220/ARMS is a Novel Modulator of Short-term Synaptic Plasticity in Hippocampal GABAergic Neurons. PLoS ONE 4, e35785.
38. Wade A, Kalmar B, Terenzio M, Garin J, Greensmith L and Schiavo G (2012) Activated leukocyte cell adhesion molecule (ALCAM) modulates neurotrophin signaling. J Neurochem, 21, 575-86.
39. Cesca F, Yabe A, Spencer-Dene B, Scholz-Starke J, Medrihan L, Maden CH, Gerhardt H, Orriss IR, Baldelli P, Al-Qatari M, Koltzenburg M, Adams RH, Benfenati F and Schiavo G (2012) Kidins220/ARMS Mediates the Integration of the Neurotrophin and VEGF Pathways in Cardiovascular and Nervous System Development. Cell Death Differ 19, 194-208.
40. Cesca F, Yabe A, Spencer-Dene B, Arrigoni A, Al-Qatari M, Henderson D, Koltzenburg M, Benfenati F and Schiavo G (2011) Kidins220/ARMS is an Essential Modulator of Cardiovascular and Nervous System Development. Cell Death Dis 2:e226.
41. Ferrari E, Maywood E, Caleo M, Restani L, Schiavo G, Pirazzini M, Rossetto O, Montecucco C, Hastings M, Niranjan D and Davletov B (2011) Re-assembled botulinum neurotoxin inhibits CNS functions without systemic toxicity. Toxins 3, 345-55.
42. Sannerud R, Declerck I, Peric A, Raemaekers T, Menendez G, Zhou L, Baert V, Coen K, Munck S, De Strooper B, Schiavo G and Annaert W (2011) ARF6 controls APP processing by mediating the endosomal sorting of BACE1. Proc Natl Acad Sci U S A 108, E559-68.
43. Goold R, Rabbanian S, Sutton L, Andre R, Arora P, Moonga J, Clarke AR, Schiavo G, Jat P, Collinge J and Tabrizi SJ (2011) Rapid cell surface prion protein conversion revealed using a novel cell system. Nat Commun 2, 281.
44. Malik B, Nirmalananthan N, Bilsland LG, La Spada AR, Hanna MG, Schiavo G, Gallo J-M and Greensmith L (2011) Absence of disturbed axonal transport in spinal and bulbar muscular atrophy. Hum Mol Genet 20, 1776-1786.
45. Granata A, Haucke V, Schiavo G* and Warner TT* (2011) CSN complex controls the stability of selected synaptic proteins via a torsinA-dependent process. EMBO J 30, 181-193. *Equal contribution.
46. Bilsland L, Sahai E, Kelly G, Golding M, Greensmith L and Schiavo G (2010) Deficits in axonal transport precede ALS symptoms in vivo. Proc Natl Acad Sci U S A 107, 20523-20528.
47. Neubrand NE, Thomas C, Schmidt S, Debant A and Schiavo G (2010) Kidins220/ARMS regulates Rac1 dependent neurite outgrowth via a direct interaction with the RhoGEF Trio. J Cell Sci 123, 2111-2123.
48. Meunier FA, Nguyen TH, Colasante C, Luo F, Sullivan RKP, Lavidis NA, Molgo J, Meriney SD and Schiavo G (2010) Sustained synaptic vesicle recycling by bulk endocytosis contributes to maintaining the high-rate neurotransmitter release stimulated by Glycerotoxin. J Cell Sci 123, 1131-1140.
49. Stevens JC, Chia R, Hendricks WT, Bros-Facer V, van Minnen J, Martin JE, Jackson GS, Greensmith L, Schiavo G and Fisher EMC (2010) Modification of superoxide dismutase 1 (SOD1) properties by a GFP tag - implications for research into amyotrophic lateral sclerosis. PLoS ONE 5, e9541.
50. Pichlmair A, Schulz O, Tan C-P, Rehwinkel J, Kato H, Takeuchi O, Akira S, Way M, Schiavo G and Reis e Sousa C (2009) Activation of MDA5 requires higher order RNA structures generated during virus infection. J Virol 83, 10761-10769.
51. Vilar M, Charalampopoulos I, Kenchappa RS, Reversi A, Applequist J, Karaca E, Simi A, Spuch C, Choi S, Friedman WJ, Ericson J, Schiavo G, Carter BD and Ibanez CF (2009) Ligand-independent signaling by genetically-crosslinked dimers of the p75 neurotrophin receptor. J Cell Sci 122, 3351-3357.
52. Hammond GRV, Schiavo G and Irvine RF (2009) Novel immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4P and PtdIns(4,5)P2. Biochem J 422, 23-35.
53. Rinaldi S, Brennan KM, Goodyear CS, O'Leary CO, Schiavo G, Crocker PR and Willison HJ. (2009) Analysis of lectin binding to glycolipid complexes using combinatorial microarrays. Glycobiology 19, 789-796.
54. Salinas S, Bilsland L, Henaff D, Weston AE, Keriel A, Schiavo G* and Kremer EJ* (2009) CAR-dependent vesicular transport of an adenovirus in primary motor neurons. PloS Pathogens 5, e1000442. *Equal contribution.
55. Ohka S, Sakai M, Bohnert S, Igarashi H, Deinhardt K, Schiavo G and Nomoto A. (2009) Receptor-dependent and -independent axonal retrograde transport of poliovirus in motor neurons. J Virol 83, 4995-5004.
56. Vilar M, Charalampopoulos I, Kenchappa RS, Simi A, Karaca E, Reversi A, Choi S, Bothwell M, Mingarro I, Friedman WJ, Schiavo G, Bastiaens PIH, Verveer PJ, Carter BD and Ibanez CF (2009) Activation of the p75 neurotrophin receptor through conformational rearrangement of disulphide-linked receptor dimers. Neuron 62, 72-83.
57. Semerdjieva S, Shortt B, Maxwell E, Sukhdeep S, Fonarev P, Hansen J, Schiavo G, Grant BD and Smythe E. (2008) Coordinated regulation of AP2 uncoating from clathrin-coated vesicles by Rab5 and hRME-6. J Cell Biol 183, 499-511.
58. Granata A, Watson R, Collinson LM, Schiavo G* and Warner TT*. (2008) The dystonia-associated protein torsinA modulates synaptic vesicles recycling. J Biol Chem 283, 7568-7579. *Equal contribution.
59. Fasano C, Campana V, Kelly G, Schulze A, Schiavo G and Zurzolo C (2008) Gene expression profile of quinacrine-cured prion-infected mouse neuronal cells. J Neurochem 105, 239-250.
60. Magnani E, Fan J, Gasparini L, Golding M, Williams M, Schiavo G, Goedert M, Amos LA and Spillantini MG (2007) Interaction of tau protein with the dynactin complex. EMBO J 26, 4546-4554.
61. Deinhardt K, Berninghausen O, Hopkins CR and Schiavo G (2007) Neurotrophins redirect p75NTR from a clathrin-independent to a clathrin-dependent endocytic pathway coupled to axonal transport. Traffic 8, 1736-1749
62. Kasperaviciute D, Weale ME, Shianna KV, Banks GT, Simpson CL, Hansen VK, Turner MR, Shaw CE, Al-Chalabi A, Pall HS, Goodall EF, Morrison KE, Orrell RW, Beck M, Jablonka S, Sendtner M, Brockington A, Ince P, Hartley J, Nixon H, Shaw P, Schiavo G, Wood NW, Goldstein DB and Fisher EM (2007) Large-scale pathways based association study in amyotrophic lateral sclerosis. Brain 30, 2292-2301.
63. Bowen S, Ateh DD, Deinhardt K, Bird MM, Price KM, Baker CS, Robson JC, Swash M, Shamsuddin W, Kawar S, El-Tawil T, Roos J, Hoyle A, Nickols CD, Knowles CK, Pullen AH, Luthert PJ, Weller RO, Hafezparast M, Franklin RJM, Revesz T, King RHM, Berninghausen O, Fisher EMC, Schiavo G and Martin JE (2007) The phagocytic capacity of neurons. Eur J Neurosci 25, 2947-2955.
64. Rigoni M, Pizzo P, Schiavo G, Weston AE, Zatti G, Caccin P, Rossetto O, Pozzan T and Montecucco M (2007) Calcium influx and mitochondrial alterations at synapses exposed to snake neurotoxins or their phospholipid hydrolysis products. J Biol Chem 282, 11238-11245.
65. Bracale A, Cesca F, Neubrand VE, Newsome TP, Way M and Schiavo G (2007) Kidins220/ARMS is transported by a kinesin-1 based mechanism likely to be involved in neuronal differentiation. Mol Biol Cell 18, 142-152.
66. Deinhardt K, Salinas S, Verastegui C, Watson R, Worth D, Hanrahan S, Bucci C and Schiavo G (2006) Rab5 and Rab7 control endocytic sorting along the axonal retrograde transport pathway. Neuron 52, 293-305.
67. Deinhardt K, Berninghausen O, Willison HJ, Hopkins CR and Schiavo G (2006) A specific clathrin-dependent endocytic pathway coupled to axonal transport in motor neurons. J Cell Biol 174, 459-471.
68. Schenning M, Proctor DT, Ragnarsson L, Barbier J, Lavidis NA, Molgó JJ, Zamponi GW, Schiavo G and Meunier FA (2006) Glycerotoxin stimulates neurotransmitter release from N-type Ca2+ channel expressing neurons. J Neurochem 98, 894-904.
69. Hammond GRV, Dove SK, Nicol A, Pinxteren JA, Zicha D and Schiavo G (2006) Hydrolysis of phosphatidylinositol (4,5)-bisphosphate is required for exocytosis from mast cells. J Cell Sci 119, 2084-2094.
70. Rigoni M, Caccin P, Gschmeissner S, Koster G, Postle AD, Rossetto O, Schiavo G and Montecucco C (2005) Equivalent effects of snake PLA2 neurotoxins and lysophospholipid-fatty acid mixtures. Science 310, 1678-1680.
71. Bohnert S and Schiavo G (2005) Tetanus toxin is transported in a novel neuronal compartment characterized by a specialized pH regulation. J Biol Chem 280, 42336-42344.
72. Salinas S, Carazo-Salas RE, Proukakis C, Cooper JM, Weston AE, Schiavo G and Warner TT (2005) Human spastin has multiple microtubule-related functions. J Neurochem 95, 1411-1420.
73. Meunier FA, Osborne SL, Hammond GR, Cooke FT, Parker PJ, Domin J and Schiavo G (2005) Phosphatidylinositol 3-kinase C2 is essential for ATP-dependent priming of neurosecretory granule exocytosis. Mol Biol Cell 16, 4841-4851.
74. Achilli F, Boyle S, Kieran D, Chia R, Hafezparast M, Martin JE, Schiavo G, Greensmith L, Bickmore W and Fisher EMC (2005) The SOD1 transgene in the G93A mouse model of amyotrophic lateral sclerosis lies on distal mouse chromosome 12. Amyotroph Lateral Scler Other Motor Neuron Disord 6, 111-114.
75. Kieran D, Hafezparast M, Bohnert S, Dick JR, Martin J, Schiavo G, Fisher EMC and Greensmith L (2005) A mutation in dynein rescues axonal transport defects and extends the life span of ALS mice. J Cell Biol 169, 561-567.
76. Parsons M, Monypenny J, Ameer-Beg SM, Millard TH, Machesky LM, Peter M, Keppler MD, Schiavo G, Watson R, Chernoff J, Zicha D, Vojnovic B and Ng T (2005) Spatially distinct binding of Cdc42 to PAK1 and N-WASP in breast carcinoma cells. Mol Cell Biol 25, 1680-1695.
77. Misbahuddin A, Placzek MR, Taanman JW, Gschmeissner S, Schiavo G, Cooper JM and Warner TT (2005) Mutant torsinA, which causes early-onset primary torsion dystonia, is redistributed to membranous structures enriched in vesicular monoamine transporter in cultured human SH-SY5Y cells. Mov Disord 20, 432-440.
78. Rigoni M, Schiavo G, Weston AE, Caccin P, Allegrini F, Pennuto M, Valtorta F, Montecucco C and Rossetto O (2004) Snake presynaptic neurotoxins with phospholipase A2 activity induce swelling of synaptic boutons and exocytosis of synaptic vesicles. J Cell Sci, 117 3561-3570.
79. Lesa GM, Palfreyman M, Hall DH, Clandinin MT, Rudolph C, Jorgensen EM and Schiavo G (2003) Long chain polyunsaturated fatty acids are required for efficient neurotransmission in C. elegans. J Cell Sci 116, 4965-4975.
80. Lalli G, Gschmeissner S and Schiavo G (2003) Myosin Va and microtubule-based motors are required for fast axonal retrograde transport of tetanus toxin in motor neurons. J Cell Sci 116, 4639-4650.
81. Jimenez JL, Smith GR, Contreras-Moreira B, Sgouros JG, Meunier FA, Bates PA and Schiavo G (2003) Functional recycling of C2 domains throughout evolution: a comparative study of synaptotagmin, protein kinase C and phospholipase C by sequence, structural and modelling approaches. J Mol Biol 333, 621-639.
82. Hafezparast M, Klocke R, Ruhrberg C, Marquardt A, Ahmad-Annuar A, Bowen S, Lalli G, Witherden AS, Hummerich H, Nicholson S, Morgan PJ, Oozageer R, Priestley JV, Averill S, King VR, Ball S, Peters J, Toda T, Yamamoto A, Hiraoka Y, Augustin M, Korthaus D, Wattler S, Wabnitz P, Dickneite C, Lampel S, Boehme F, Peraus G, Popp A, Rudelius M, Schlegel J, Fuchs H, Hrabe de Angelis M, Schiavo G, Shima DT, Russ AP, Stumm G, Martin JE and Fisher EMC (2003) Mutations in dynein link motor neuron degeneration to defects in retrograde transport. Science, 300, 808-812.
83. Caccin P, Rossetto O, Rigoni M, Johnson E, Schiavo G and Montecucco C (2003) VAMP/synaptobrevin cleavage by tetanus and botulinum neurotoxins is strongly enhanced by acidic liposomes. FEBS Lett 542, 132-136.
84. Meunier FA, Feng ZP, Molgó J, Zamponi GW and Schiavo G (2002) Glycerotoxin from Glycera convoluta stimulates neurosecretion by up-regulating N-type Ca2+ channel activity. Embo J 21, 6733-6743.
85. Herreros J and Schiavo G (2002) Lipid microdomains are involved in neurospecific binding and internalisation of clostridial neurotoxins. Int J Med Microbiol 291, 447-453.
86. Lalli G and Schiavo G (2002) Analysis of retrograde transport in motor neurons reveals common endocytic carriers for tetanus toxin and neurotrophin receptor p75NTR. J Cell Biol 156, 233-239.
87. Hawkes NA, Otero G, Winkler GS, Marshall N, Dahmus ME, Krappmann D, Scheidereit C, Thomas CL, Schiavo G, Erdjument-Bromage H, Tempst P and Svejstrup JQ (2002) Purification and characterization of the human elongator complex. J Biol Chem 277, 3047-3052.
88. Herreros J, Ng T and Schiavo G (2001) Lipid rafts act as specialized domains for tetanus toxin binding and internalization into neurons. Mol Biol Cell 12, 2947-2960.
89. Coppola T, Magnin-Luthi S, Perret-Menoud V, Gattesco S, Schiavo G and Regazzi R (2001) Direct interaction of the Rab3 effector RIM with Ca2+ channels, SNAP-25, and synaptotagmin. J Biol Chem 276, 32756-32762.
90. Kittler JT, Rostaing P, Schiavo G, Fritschy JM, Olsen R, Triller A and Moss SJ (2001) The subcellular distribution of GABARAP and its ability to interact with NSF suggest a role for this protein in the intracellular transport of GABA(A) receptors. Mol Cell Neurosci 18, 13-25.
91. Osborne SL, Thomas CL, Gschmeissner S and Schiavo G (2001) Nuclear PtdIns(4,5)P2 assembles in a mitotically regulated particle involved in pre-mRNA splicing. J Cell Sci, 114, 2501-2511.
92. Iglesias T, Cabrera-Poch N, Mitchell MP, Naven TJ, Rozengurt E and Schiavo G (2000) Identification and cloning of Kidins220, a novel neuronal substrate of protein kinase D. J Biol Chem 275, 40048-40056.
93. Sinha K, Box M, Lalli G, Schiavo G, Schneider H, Groves M, Siligardi G and Fairweather N (2000) Analysis of mutants of tetanus toxin Hc fragment: ganglioside binding, cell binding and retrograde axonal transport properties. Mol Microbiol 37, 1041-1051.
94. Herreros J, Lalli G and Schiavo G (2000) C-terminal half of tetanus toxin fragment C is sufficient for neuronal binding and interaction with a putative protein receptor. Biochem J 347, 199-204.
95. Herreros J, Lalli G, Montecucco C and Schiavo G (2000) Tetanus toxin fragment C binds to a protein present in neuronal cell lines and motoneurons. J Neurochem 74, 1941-1950.
96. Muller JM, Rabouille C, Newman R, Shorter J, Freemont P, Schiavo G, Warren G and Shima DT. (1999) An NSF function distinct from ATPase-dependent SNARE disassembly is essential for Golgi membrane fusion. Nat Cell Biol, 1, 335-340.
97. Lalli G, Herreros J, Osborne SL, Montecucco C, Rossetto O and Schiavo G (1999) Functional characterisation of tetanus and botulinum neurotoxins binding domains. J Cell Sci 112, 2715-2724.
98. Thomas CL, Steel J, Prestwich GD and Schiavo G (1999) Generation of phosphatidylinositol-specific antibodies and their characterization. Biochem Soc Trans 27, 648-652.
99. Osborne SL, Herreros J, Bastiaens PI and Schiavo (1999) Calcium-dependent oligomerization of synaptotagmins I and II. Synaptotagmins I and II are localized on the same synaptic vesicle and heterodimerize in the presence of calcium. J Biol Chem 274, 59-66.
100. Stamnes M, Schiavo G, Stenbeck G, Sollner TH and Rothman JE (1998) ADP-ribosylation factor and phosphatidic acid levels in Golgi membranes during budding of coatomer-coated vesicles. Proc Natl Acad Sci U S A 95, 13676-13680.
101. Tonello F, Schiavo G and Montecucco C (1997) Metal substitution of tetanus neurotoxin. Biochem J 322, 507-510.
102. Schiavo G, Stenbeck G, Rothman JE and Sollner TH (1997) Binding of the synaptic vesicle v-SNARE, synaptotagmin, to the plasma membrane t-SNARE, SNAP-25, can explain docked vesicles at neurotoxin-treated synapses. Proc Natl Acad Sci U S A 94, 997-100.
103. Schiavo G, Gu QM, Prestwich GD, Sollner TH and Rothman JE (1996) Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagmin. Proc Natl Acad Sci U S A 93, 13327-13332.
104. Matteoli M, Verderio C, Rossetto O, Lezzi N, Coco S, Schiavo G and Montecucco C (1996) Synaptic vesicle endocytosis mediates the entry of tetanus neurotoxin into hippocampal neurons. Proc Natl Acad Sci U S A 93, 13310-13315.
105. Osen-Sand A, Staple JK, Naldi E, Schiavo G, Rossetto O, Petitpierre S, Malgaroli A, Montecucco C and Catsicas S (1996) Common and distinct fusion proteins in axonal growth and transmitter release. J Comp Neurol 367, 222-234.
106. Morante S, Furenlid L, Schiavo G, Tonello F, Zwilling R and Montecucco C (1996) X-ray absorption spectroscopy study of zinc coordination in tetanus neurotoxin, astacin, alkaline protease and thermolysin. Eur J Biochem 235, 606-612.
107. Rossetto O, Gorza L, Schiavo G, Schiavo N, Scheller RH and Montecucco C (1996) VAMP/synaptobrevin isoforms 1 and 2 are widely and differentially expressed in nonneuronal tissues. J Cell Biol 132, 167-179.
108. Schiavo G, Gmachl MJ, Stenbeck G, Sollner TH and Rothman JE (1995) A possible docking and fusion particle for synaptic transmission. Nature 378, 733-736.
109. Schiavo G and Montecucco C (1995) Tetanus and botulism neurotoxins: isolation and assay. Methods Enzymol 248, 643-652.
110. Nielander HB, Onofri F, Valtorta F, Schiavo G, Montecucco C, Greengard P and Benfenati F (1995) Phosphorylation of VAMP/synaptobrevin in synaptic vesicles by endogenous protein kinases. J Neurochem 65, 1712-1720.
111. De Filippis V, Vangelista L, Schiavo G, Tonello F and Montecucco C (1995) Structural studies on the zinc-endopeptidase light chain of tetanus neurotoxin. Eur J Biochem 229, 61-69.
112. Schiavo G, Shone CC, Bennett MK, Scheller RH and Montecucco C. (1995) Botulinum neurotoxin type C cleaves a single Lys-Ala bond within the carboxyl-terminal region of syntaxins. J Biol Chem 270, 10566-10570.
113. Washbourne P, Schiavo G and Montecucco C (1995) Vesicle-associated membrane protein-2 (synaptobrevin-2) forms a complex with synaptophysin. Biochem J 305, 721-724.
114. Kochi SK, Schiavo G, Mock M and Montecucco C (1994) Zinc content of the Bacillus anthracis lethal factor. FEMS Microbiol Lett 124, 343-348.
115. Rossetto O, Schiavo G, Montecucco C, Poulain B, Deloye F, Lozzi L and Shone CC (1994) SNARE motif and neurotoxins. Nature 372, 415-416.
116. Schiavo G, Malizio C, Trimble WS, Polverino de Laureto P, Milan G, Sugiyama H, Johnson EA and Montecucco C (1994) Botulinum G neurotoxin cleaves VAMP/synaptobrevin at a single Ala-Ala peptide bond. J Biol Chem 269, 20213-20216.
117. Kochi SK, Martin I, Schiavo G, Mock M and Cabiaux V (1994) The effects of pH on the interaction of anthrax toxin lethal and edema factors with phospholipid vesicles. Biochemistry 33, 2604-2609.
118. de Paiva A, Ashton AC, Foran P, Schiavo G, Montecucco C and Dolly JO (1993) Botulinum A like type B and tetanus toxins fulfils criteria for being a zinc-dependent protease. J Neurochem 61, 2338-2341.
119. Schiavo G, Santucci A, Dasgupta BR, Mehta PP, Jontes J, Benfenati F, Wilson MC and Montecucco C (1993) Botulinum neurotoxins serotypes A and E cleave SNAP-25 at distinct COOH-terminal peptide bonds. FEBS Lett 335, 99-103.
120. Schiavo G, Rossetto O, Catsicas S, Polverino de Laureto P, DasGupta BR, Benfenati F and Montecucco C (1993) Identification of the nerve terminal targets of botulinum neurotoxin serotypes A, D, and E. J Biol Chem 268, 23784-23787.
121. Onaderra M, Mancheno JM, Gasset M, Lacadena J, Schiavo G, Martinez del Pozo A and Gavilanes JG (1993) Translocation of -sarcin across the lipid bilayer of asolectin vesicles. Biochem J 295, 221-225.
122. Poulain B, Rossetto O, Deloye F, Schiavo G, Tauc L and Montecucco C (1993) Antibodies against rat brain vesicle-associated membrane protein (synaptobrevin) prevent inhibition of acetylcholine release by tetanus toxin or botulinum neurotoxin type B. J Neurochem 61, 1175-1178.
123. Patarnello T, Bargelloni L, Rossetto O, Schiavo G and Montecucco C (1993) Neurotransmission and secretion. Nature 364, 581-582.
124. Schiavo G, Shone CC, Rossetto O, Alexander FC and Montecucco C (1993) Botulinum neurotoxin serotype F is a zinc endopeptidase specific for VAMP/synaptobrevin. J Biol Chem 268, 11516-11519.
125. Schiavo G, Rossetto O, Santucci A, DasGupta BR and Montecucco C (1992) Botulinum neurotoxins are zinc proteins. J Biol Chem 267, 23479-23483.
126. Schiavo G, Benfenati F, Poulain B, Rossetto O, Polverino de Laureto P, DasGupta BR and Montecucco C (1992) Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin. Nature 359, 832-835.
127. Schiavo G, Poulain B, Rossetto O, Benfenati F, Tauc L and Montecucco C (1992) Tetanus toxin is a zinc protein and its inhibition of neurotransmitter release and protease activity depend on zinc. EMBO J 11, 3577-3583.
128. Calappi E, Masserini M, Schiavo G, Montecucco C and Tettamanti G (1992) Lipid interaction of tetanus neurotoxin. A calorimetric and fluorescence spectroscopy study. FEBS Lett 309, 107-110.
129. Rossetto O, Schiavo G, Polverino de Laureto P, Fabbiani S and Montecucco C (1992) Surface topography of histidine residues of tetanus toxin probed by immobilized-metal-ion affinity chromatography. Biochem J 285, 9-12.
130. Amadori A, De Silvestro G, Zamarchi R, Veronese ML, Mazza MR, Schiavo G, Panozzo M, De Rossi A, Ometto L, Mous J, Barelli A, Borri A, Salmaso L and Chieco-Bianchi L (1992) CD4 epitope masking by gp120/anti-gp120 antibody complexes. A potential mechanism for CD4+ cell function down-regulation in AIDS patients. J Immunol 148, 2709-2716.
131. Schiavo G, Ferrari G, Rossetto O and Montecucco C (1991) Tetanus toxin receptor. Specific cross-linking of tetanus toxin to a protein of NGF-differentiated PC 12 cells. FEBS Lett 290, 227-230.
132. Massari S, Folena E, Ambrosin V, Schiavo G and Colonna R (1991) pH-dependent lipid packing, membrane permeability and fusion in phosphatidylcholine vesicles. Biochim Biophys Acta 1067, 131-138.
133. Gasset M, Onaderra M, Martinez del Pozo A, Schiavo G, Laynez J, Usobiaga P and Gavilanes JG (1991) Effect of the antitumour protein alpha-sarcin on the thermotropic behaviour of acid phospholipid vesicles. Biochim Biophys Acta 1068, 9-16.
134. Schiavo G, Demel R and Montecucco C (1991) On the role of polysialoglycosphingolipids as tetanus toxin receptors. A study with lipid monolayers. Eur J Biochem 199, 705-711.
135. Demel R, Schiavo G, de Kruijff B and Montecucco C (1991) Lipid interaction of diphtheria toxin and mutants. A study with phospholipid and protein monolayers. Eur J Biochem 197, 481-486. 
136. Papini E, Santucci A, Schiavo G, Domenighini M, Neri P, Rappuoli R and Montecucco C (1991) Tyrosine-65 is photolabelled by 8-azidoadenine and 8-azidoadenosine at the NAD+ binding site of diphtheria toxin. J Biol Chem 266, 2494-2498.
137. Schiavo G, Papini E, Genna G and Montecucco C (1990) An intact interchain disulfide bond is required for the neurotoxicity of tetanus toxin. Infect Immun 58, 4136-4141.
138. Schiavo G, Boquet P, Dasgupta BR and Montecucco C (1990) Membrane interactions of tetanus and botulinum neurotoxins: a photolabelling study with photoactivatable phospholipids. J Physiol (Paris) 84, 180-187.
139. Singh BR, Fuller MP and Schiavo G (1990) Molecular structure of tetanus neurotoxin as revealed by Fourier transform infrared and circular dichroic spectroscopy. Biophys Chem 36, 155-166.
140. Dabbeni-Sala F, Schiavo G and Palatini P (1990) Mechanism of local anesthetic effect on mitochondrial ATP synthase as deduced from photolabelling and inhibition studies with phenothiazine derivatives. Biochim Biophys Acta 1026, 117-125.
141. Papini E, Schiavo G, Rappuoli R and Montecucco C (1990) Histidine-21 is involved in diphtheria toxin NAD+ binding. Toxicon 28, 631-635. 
142. Capaldi RA, Zhang YZ, Rizzuto R, Sandona D, Schiavo G and Bisson R (1990) The two oxygen-regulated subunits of cytochrome c oxidase in Dictyostelium discoideum derive from a common ancestor. FEBS Lett 261, 158-160.
143. Papini E, Schiavo G, Sandona D, Rappuoli R and Montecucco C (1989) Histidine 21 is at the NAD+ binding site of diphtheria toxin. J Biol Chem 264, 12385-12388.
144. Schiavo G and Bisson R (1989) Oxygen influences the subunit structure of cytochrome c oxidase in the slime mold Dictyostelium discoideum. J Biol Chem 264, 7129-7134.
145. Montecucco C, Schiavo G and Dasgupta BR (1989) Effect of pH on the interaction of botulinum neurotoxins A, B and E with liposomes. Biochem J 259, 47-53.
146. Sonnino S, Acquotti D, Chigorno V, Pitto M, Montecucco C, Schiavo G, Kirschner G and Tettamanti G (1988) Recent advances in the chemistry and technology of gangliosides. Indian J Biochem Biophys 25, 144-149.
147. Montecucco C, Schiavo G, Gao Z, Bauerlein E, Boquet P and DasGupta BR (1988) Interaction of botulinum and tetanus toxins with the lipid bilayer surface. Biochem J 251, 379-383.
148. Moscufo N, Gallina A, Schiavo G, Montecucco C and Tomasi M (1987) Multiple lipid interactions of the Sendai virus fusogenic protein. J Biol Chem 262, 11490-11496.
149. Papini E, Schiavo G, Tomasi M, Colombatti M, Rappuoli R and Montecucco C (1987) Lipid interaction of diphtheria toxin and mutants with altered fragment B. 2. Hydrophobic photolabelling and cell intoxication. Eur J Biochem 169, 637-644.
150. Montecucco C, Schiavo G, Bacci B and Bisson R (1987) Isolation and characterization of cytochrome c oxidase from bird and fish heart mitochondria. Comp Biochem Physiol B 87, 851-856.
151. Bisson R, Schiavo G and Montecucco C (1987) ATP induces conformational changes in mitochondrial cytochrome c oxidase. Effect on the cytochrome c binding site. J Biol Chem 262, 5992-5998.
152. Papini E, Colonna R, Schiavo G, Cusinato F, Tomasi M, Rappuoli R and Montecucco C (1987) Diphtheria toxin and its mutant crm197 differ in their interaction with lipids. FEBS Lett 215, 73-78.
153. Bisson R and Schiavo G (1986) Two different forms of cytochrome c oxidase can be purified from the slime mold Dictyostelium discoideum. J Biol Chem 261, 4373-4376.
154. Degli Esposti M, Avitabile E, Barilli M, Schiavo G, Montecucco C and Lenaz G (1986) Comparative biochemistry of the ubiquinol-cytochrome c oxidoreductase (EC 1.10.2.2) isolated from different heart mitochondria. Comp Biochem Physiol B 85, 543-552.
155. Montecucco C, Tomasi M, Schiavo G and Rappuoli R (1986) Hydrophobic photolabelling of pertussis toxin subunits interacting with lipids. FEBS Lett 194, 301-304.
156. Montecucco C, Schiavo G, Brunner J, Duflot E, Boquet P and Roa M (1986) Tetanus toxin is labelled with photoactivatable phospholipids at low pH. Biochemistry 25, 919-924.
157. Montecucco C and Schiavo G (1986) 1-Palmitoyl-2-(p-benzoyl)benzoyl phosphatidylcholine, a photoactive phospholipid for the labelling of membrane components. Biochem J 237, 309-312.
158. Montecucco C, Schiavo G and Bisson R (1986) ATP binding to bovine heart cytochrome c oxidase. A photoaffinity labelling study. Biochem J 234, 241-243.
159. Bisson R, Schiavo G and Papini E. (1985) Cytochrome c oxidase from the slime mold Dictyostelium discoideum: purification and characterization. Biochemistry, 24, 7845-7852.
160. Montecucco C, Schiavo G and Tomasi M (1985) pH-dependence of the phospholipid interaction of diphtheria-toxin fragments. Biochem J 231, 123-128.
Research Papers (as authors' consortium)
161. Creutz CE, Moss S, Edwardson JM, Hide I, Gomperts B and Participants of the EMBO Course "Advanced Techniques for Studying Secretion" (1992) Differential recognition of secretory vesicles by annexins. Biochem Biophys Res Commun 184, 347-52.
Reviews and Book Chapters
1. Villarroel-Campos D, Schiavo G and Lazo OM (2018) The many disguises of the signalling endosome. FEBS Lett, 592, 3615-3632.
2. Cesca F, Schiavo G and Benfenati F (2018) Kidins220/ARMS transgenic lines could be instrumental to the understanding of the molecular mechanisms leading to spastic paraplegia and obesity. Eur J Neurol 25, e107.
3. Terenzio M, Schiavo G and Fainzilber M (2017) Compartmentalized Signaling in Neurons: from Cell Biology to Neuroscience. Neuron 96, 667-679.
4. Surana S, Tosolini AP, Meyer IF, Fellows AD, Novoselov S and Schiavo G (2017) The travel diaries of tetanus and botulinum neuroxins. Toxicon, doi: 10.1016/j.toxicon.2017.10.008.
5. Sleigh JN, Vagnoni A, Twelvetrees AE and Schiavo G (2017) Methodological advances in imaging intravital axonal transport. F1000Res 6, 200.
6. Gibbs K, Greensmith L and Schiavo G (2015) Regulation of axonal transport by protein kinases. Trend Biochem Sci 40, 597-610.
7. Schmieg N, Bercsenyi K and Schiavo G (2015) Uptake and transport of clostridium neurotoxins. In "The comprehensive sourcebook of bacterial protein toxins." 4th Ed, JE Alouf, D Ladant and MR Popoff Eds, Elsevier, Oxford (UK) 337-360.
8. Debaisieux S and Schiavo G (2014) TiME for TMEM106B. EMBO J 33, 405-6.
9. Schmieg N, Menendez G, Schiavo G and Terenzio M (2014) Signalling endosomes in axonal transport: travel updates on the molecular highway. Sem Cell Biol 27, 32-43.
10. Cesca F, Schiavo G and Benfenati F (2013) Novel experimental models to study neurotrophin function. Eur J Neurodegen Dis 2, 89-99.
11. Schiavo G, Greensmith L, Hafezparast M and Fisher EMC (2013) Cytoplasmic dynein heavy chain: the servant of many masters. Trends Neurosci 36, 641-51.
12. Schiavo G and Fainzilber M (2013) Alternative energy for neuronal motors. Nature 495, 178-180.
13. Chancellor MB, Elovic E, Esquenazi A, Naumann M, Segal KR, Schiavo G, Smith CP and Ward AB (2013) Evidence-based review and assessment of botulinum neurotoxin for the treatment of urologic conditions. Toxicon 67, 129-40.
14. Naumann M, Dressler D, Hallett M, Jankovic J, Schiavo G, Segal KR, Truong D (2013) Evidence-based review and assessment of botulinum neurotoxin for the treatment of secretory disorders. Toxicon 67, 141-52.
15. Thige AP and Schiavo G (2013) Botulinum neurotoxins: mechanism of action. Toxicon 67, 87-93.
16. Bercsenyi K, Giribaldi F and Schiavo G (2013) The elusive compass of clostridial neurotoxins: deciding when and where to go. Curr Top Microbiol Immunol 364, 91-113.
17. Neubrand VE, Cesca F, Benfenati F and Schiavo G (2012) Kidins220/ARMS as functional mediator of multiple receptor signalling pathways. J Cell Sci 125, 1-10.
18. Kuta A, Hafezparast M, Schiavo G and Fisher EMC (2012) Genetic insights into mammalian cytoplasmic dynein function provided by novel mutations in mouse. In "Dyneins." S King Ed, Academic Press, London (UK) 483-504.
19. Salinas S, Schiavo G and Kremer EJ (2010) The hitchhiker's guide to the nervous system: axonal transport of neurotropic viruses and toxins. Nat Rev Microbiol 8, 645-55.
20. Terenzio M and Schiavo G (2010) The more, the better: the BICD family gets bigger. EMBO J 29, 1625-1626.
21. Warner TT, Schiavo G and Granata A (2010) TorsinA and DYT1 dystonia: a synaptopathy? Biochem Soc Trans 38, 452-456.
22. Granata A, Schiavo G and Warner TT (2009) TorsinA and Dystonia: from nuclear envelope to synapse. J Neurochem 109, 1596-1609.
23. Caleo M and Schiavo G (2009) Central effects of tetanus and botulinum neurotoxins. Toxicon 54, 593-599.
24. Bilsland LG and Schiavo G (2008) Axonal transport tracers. In "The New Encyclopedia of Neuroscience." LR Squire Ed, Academic Press, Oxford (UK) 1209-1216.
25. Tooze SA and Schiavo G (2008) Liaisons dangereuses: autophagy, neuronal survival and neurodegeneration. Curr Opin Neurobiol 18, 504-515.
26. Salinas S, Bilsland LG and Schiavo G (2008) Molecular landmarks along the axonal route: axonal transport in health and disease. Curr Opin Cell Biol 20, 445-453.
27. Salinas S, Carazo-Salas RE, Proukakis C, Schiavo G and Warner TT (2007) Spastin and microtubules: functions in health and disease. J Neurosci Res 85, 2778-2782.
28. Hammond GRV and Schiavo G (2007) The phosphoinositides: Under-PPIning synaptic function in health and disease. Dev Neurobiol 67, 1232-1247.
29. Schiavo G (2006) Dangerous liaisons on neurons. Nature, 444, 1019-1020.
30. Bohnert S, Deinhardt K, Salinas S and Schiavo G. (2006) Uptake and transport of clostridium neurotoxins. In "The comprehensive sourcebook of bacterial protein toxins." 3rd Ed, JE Alouf and MR Popoff Eds, Academic Press, London (UK) 390-408.
31. Montecucco C, Schiavo G and Pantano S (2005) SNARE complexes and neuroexocytosis: how many, how close? Trends Biol Sci 30, 367-372.
32. Deinhardt K and Schiavo G (2005) Endocytosis and retrograde axonal traffic in motor neurons. Biochem Soc Trans 72, 139-150.
33. Montecucco C, Rossetto O and Schiavo G (2004) Presynaptic receptor arrays for clostridial neurotoxins. Trends Microbiol 12, 442-446.
34. Schiavo G and Chao MV (2004) Motors, adaptors, and receptors: Key elements of neuronal transport. J Neurobiol 58, 161-163.
35. Hammond G, Thomas CL and Schiavo G (2004) Nuclear phosphoinositides and their functions. Curr Top Microbiol Immunol 282, 177-206.
36. Lalli G, Bohnert S, Verastegui C and Schiavo G (2003) The journey of tetanus and botulinum neurotoxins in neurons. Trends Microbiol 11, 431-437.
37. Verastegui C, Lalli G, Bohnert S, Meunier FA and Schiavo G (2002) Clostridial neurotoxin. J Toxicol: Toxin Rev 21, 203-227.
38. Lalli G, Herreros J and Schiavo G. (2002) Neurospecific binding and trafficking of tetanus toxin. In "Scientific and Therapeutic Aspects of Botulinum Toxin" M Brin, M Hallett and J Jankovic Eds, Lippincott, Williams & Wilkins, New York (NY) 49-59.
39. Meunier FA, Schiavo G and Molgo J (2002) Botulinum neurotoxins: from paralysis to recovery of functional neuromuscular transmission. J Physiol (Paris) 96, 105-113.
40. Meunier FA, Herreros J, Schiavo G, Poulain B and Molgo J. (2002) Molecular mechanism of action of botulinal neurotoxins and the synaptic remodeling they induce in vivo at the skeletal neuromuscular junction. In "Neurotoxicology Handbook Vol. I" EJ Massaro Ed, Humana Press, Totowa (NJ) 305-347.
41. Rossetto O, Schiavo G and Montecucco C. (2001) Clostridium tetani. In "Molecular Medical Microbiology" M Sussman Ed, Academic Press, London (UK) 1905-1919.
42. Osborne SL, Meunier FA and Schiavo G (2001) Phosphoinositides as key regulators of synaptic function. Neuron 32, 9-12.
43. Schiavo G and Van Der Goot FG (2001) The Bacterial Toxin Toolkit. Nat Rev Mol Cell Biol 2, 530-538.
44. Rossetto O, Seveso M. Caccin P, Schiavo G and Montecucco C (2001) Tetanus and botulinum neurotoxins: turning bad guys into good by research. Toxicon 39, 27-41.
45. Schiavo G, Matteoli M and Montecucco C (2000) Neurotoxins and neuroexocytosis. Physiol Rev 80, 717-766.
46. Rossetto O, De Bernard M, Pellizzari R, Vitale G, Schiavo G and Montecucco C (2000) Bacterial toxins with intracellular protease activity. Clin Chim Acta 291, 189-199.
47. Schiavo G and Montecucco C (2000) Tossine batteriche. In "Tossicologia Molecolare e cellulare" Cantelli Forti G, Galli CL, Hrelia P and Marinovich M Eds, UTET, Torino (I) 149-159.
48. Owen DJ and Schiavo G (1999) A handle on NSF. Nat Cell Biol 1, E127-E128.
49. O'Kane CJ, Schiavo G and Sweeney ST (1999) Toxins that affect neurotransmitter release. In "Neurotransmitter release" H Bellen Ed, Oxford University Press, Oxford (UK) 208-236.
50. Schiavo G, Herreros J, Iglesias T, Lalli G, Osborne SL and Thomas CL (1999) Molecular analysis of regulated secretion. In NATO ASI Series "Molecular mechanism of transcellular signalling" JP Thiery Ed, IOS Press, Amsterdam (NL) 309, 221-235.
51. Herreros J, Lalli G, Montecucco C and Schiavo G (1999) Pathophysiological properties and mechanisms of action of clostridial neurotoxins. In "The comprehensive Sourcebook of bacterial Protein Toxins." 2rd Ed JE Alouf and JH Freer Eds, Academic Press, London (UK) 202-228.
52. Pellizzari R, Rossetto O, Schiavo G and Montecucco C (1999) Tetanus and botulinum neurotoxins: mechanism of action and therapeutic uses. Philos Trans R Soc Lond B 354, 259-268.
53. Montecucco C, Pellizzari R, Rossetto O, Schiavo G, Tonello F, Washbourne P (1998) Clostridial neurotoxins as enzymes: structure and function. In "Cellular and molecular mechanisms of toxin action. Secretory systems and toxin". M Linial, A Grasso, P Lazarovici Eds, Harwood Academic Publishers, Amsterdam (NL) 324-341.
54. Schiavo G and Stenbeck G (1998) Molecular analysis of neurotransmitter release. Essay Biochem 33, 27-39.
55. Schiavo G, Osborne SL and Sgouros JG (1998) Synaptotagmins: more isoforms than functions. Biochem Biophys Res Commun 248, 1-8.
56. Schiavo G (1997) The "face" of VacA. Trends Microbiol 5, 477.
57. Schiavo G (1997) Il ruolo della sinaptotagmina nel terminale sinaptico. Biotech 3, 17-22.
58. Schiavo G and Montecucco C (1997) Structure and mode of action of botulinum and tetanus neurotoxins. In "The Clostridia: Molecular genetics and pathogenesis" J Rood, B McClane, G Songer and R Titball Eds, Academic Press, London (UK) 295-322.
59. Schiavo G and Montecucco C (1997) Clostridial neurotoxins. In "Bacterial toxins. Tools in Cell Biology and Pharmacology" K Aktories Ed, Chapman & Hall, Weinheim (D) 169-192.
60. Schiavo G (1997) VAMP-specific botulinum neurotoxins. In "Guidebook to protein toxins and their use in cell biology" C Montecucco and R Rappuoli Eds, Oxford University Press, Oxford (UK) 101-103.
61. Pellizzari R, Tonello F, Washbourne P, Morante S, Rossetto O, Schiavo G and Montecucco C (1996) The metalloproteinase activity of clostridial neurotoxins. In "Biomedical aspects of clostridial neurotoxins" HS Tranter Ed, CAMR, Porton Down (UK) 49-54.
62. Montecucco C, Papini E and Schiavo G (1996) Bacterial protein toxins and cell vesicle trafficking. Experientia 52, 1026-1032.
63. Schiavo G, Rossetto O and Montecucco C (1996) Tetanus and botulism neurotoxins. In "Zinc metalloproteases in health and diseases" NH Hooper Ed, Taylor & Francis Publ, London (UK) 205-220.
64. Tonello F, Morante S, Rossetto O, Schiavo G, and Montecucco C (1996) Tetanus and botulinum neurotoxins. A novel group of zinc-endopeptidases. Adv Exp Med Biol 389, 251-260.
65. Rossetto O, Osen-Sand A, Catsicas S, Naldi E, Malgaroli A, Schiavo G and Montecucco C (1996) Cleavage of SNARE proteins is correlated to inhibition of neuroexocytosis by tetanus and botulinum neurotoxins and SNARE proteins are present in non neuronal tissues. In "Bacterial Protein Toxins" Zlb Bakt Suppl, Gustav Fisher Verlag, Stuttgart (D) 28, 260-268.
66. Montecucco C, Schiavo G, Tugnoli V and De Grandis D (1996) Botulinum neurotoxins: mechanism of action and therapeutic applications. Mol Medicine Today 2, 418-424.
67. Deloye F, Schiavo G, Doussau F, Rossetto O, Montecucco C and Poulain B (1996) Modes d'action moleculaire des neurotoxines botuliques et tetanique. M S-Med Sci 12,175-182.
68. Schiavo G, Rossetto O and Montecucco C (1996) The mechanism of action of tetanus and botulinum neurotoxins. In "Toxicology-From cells to man" Arch Toxicol, Springer, Berlin (D) 18, 342-354.
69. Schiavo G, Rossetto O and Montecucco C (1993) Bases moleculares del tétanos y del botulismo. Investigación y Ciencia: Edición Española de Scientific American 234, 46-55.
70. Montecucco C and Schiavo G (1995) Structure and function of tetanus and botulinum neurotoxins. Q Rev Biophys 28 423-472.
71. Montecucco C, Schiavo G, Papini E, Rossetto O, De Bernard M, Tonello F, Moll GN and Washbourne PE (1995) Translocation of bacterial protein toxins across membranes. In "Biochemistry of cell membranes. A compendium of selected topics" S Papa and J Tager Eds, Birkhauser Verlag AG, Basel (CH) 75-93.
72. Schiavo G, Rossetto O, Morante S, Tonello F, Pellizzari R and Montecucco C (1995) Tetanus and botulinum neurotoxins: a new group of metallo-proteinases. Biochimica in Italia 3, 27-43.
73. Rossetto O, Deloye F, Poulain B, Pellizzari R, Schiavo G and Montecucco C (1995) The metallo-protease activity of tetanus and botulinum neurotoxins. J Physiol (Paris) 89, 43-50.
74. Schiavo G, Rossetto O, Tonello F and Montecucco C (1995) Intracellular targets and metalloprotease activity of tetanus and botulism neurotoxins. Curr Top Microbiol Immunol 195, 257-274.
75. Montecucco C and Schiavo G (1994) Inhibition of neuroexocytosis by tetanus and botulism neurotoxins. Seminar Cell Biol 5, 221-229.
76. Schiavo G, Rossetto O and Montecucco C (1994) Mechanism of action of tetanus and botulism neurotoxins. Mol Microbiol 13, 1-8.
77. Menestrina G, Schiavo G and Montecucco C (1994) Molecular mechanism of action of bacterial protein toxins. Mol Aspects Med 15, 79-193
78. Montecucco C, Papini E and Schiavo G (1994) Bacterial protein toxins penetrate cells via a four-step mechanism. FEBS Lett 346, 92-98.
79. Schiavo G and Montecucco C (1994) "Response to: JA Coffield, RA Considine and LL Simpson "Clostridial neurotoxins in the age of molecular medicine". Trends Microbiol 2, 67.
80. Schiavo G, Benfenati F, Poulain B, Rossetto O, Shone CC, Dasgupta BR and Montecucco C (1994) Tetanus and botulinum neurotoxins are zinc proteases specific for proteins involved in vesicle docking and fusion. In "Bacterial Protein Toxins" Zlb Bakt Suppl, Gustav Fisher Verlag, Stuttgart (D) 24, 375-385.
81. Schiavo G, Rossetto O, Benfenati F, Poulain B and Montecucco C (1994) Tetanus and botulinum neurotoxins are zinc proteases specific for components of the neuroexocytosis apparatus. Annals NY Acad Sci 710, 65-76.
82. Schiavo G, Rossetto O, and Montecucco C. (1993) Il meccanismo di azione delle neurotossine responsabili del tetano e del botulismo. ORIS Medicina 8, 46-49.
83. Schiavo G, Rossetto O and Montecucco C (1993) Tetano e botulismo. Le Scienze (italian edition of Scientific American) 304, 40-48.
84. Schiavo G, Rossetto O, Ferrari G and Montecucco C (1993) The neurospecific binding of tetanus toxin is mediated by a 20 kDa protein and by acidic lipids. In "Botulinum and tetanus neurotoxins: neurotransmission and biomedical aspects" BR DasGupta Ed, Plenum Publ Co, New York (NY) 221-230.
85. Rossetto O, Schiavo G, Benfenati F and Montecucco C (1993) Le neurotossine del tetano e del botulismo sono zinco proteasi neurospecifiche. Acta Med Rom 31, 289-296.
86. Montecucco C. and Schiavo G (1993) Tetanus and botulism neurotoxins: a new group of zinc proteases. Trends Biochem Sci 18, 324-329.
87. Schiavo G, Poulain B, Benfenati F, Dasgupta BR and Montecucco C (1993) Novel targets and catalytic activities of bacterial protein toxins. Trends Microbiol 1, 170-174.
88. Montecucco C and Schiavo G (1993) Le tossine del tetano e del botulismo sono due zinco-proteasi a bersaglio nervoso. Biotech 8, 44-47.
89. Montecucco C, Papini E, Schiavo G, Padovan E and Rossetto O (1992) Ion channel and membrane translocation of diphtheria toxin. FEMS Microbiol Immunol 105, 101-112.
90. Montecucco C, Papini E, Domenighini M, Schiavo G and Rappuoli R. (1992) Structure and NAD+ binding of diphtheria toxin fragment A. In "Bacterial Protein Toxins" Zlb Bakt Suppl, Gustav Fisher Verlag, Stuttgart (D) 23, 315-321.
91. Montecucco C, Schiavo G, Papini E, and Bisson R (1991) Photolabelling of membrane proteins with photoactive phospholipids. In "Recent advances in biochemistry" SM Byun, SY Lee and CH Yang Eds, The Biochemical Society of the Republic of Korea, Seoul (K) 93-107.
92. Montecucco C, Papini E and Schiavo G (1991) Molecular models of toxin membrane translocation. In "Sourcebook of bacterial protein toxin" JE Alouf and JH Freer Eds, Academic Press, New York (NY) 45-56.
93. Montecucco C, Papini E, Schiavo G, Sandona D and Rappuoli R (1990) On the cellular mechanism of action of diphtheria toxin. In "Organelles in eukaryotic cells: molecular structure and interactions" JM Tager, A Azzi, S Papa and F Guerrieri Eds, Plenum Press, New York (NY) 115-125
94. Montecucco C, Schiavo G, Papini E, Tomasi M and Bisson R (1989) Membrane protein labelling with photoreactive phospolipid analogues. In NATO ASI Series "Photochemical Probes in Biochemistry" PE Nielsen Ed, Kluwer Academic Publishers, Dordrecht (NL) 272, 43-58.
95. Bisson R and Schiavo G (1989) Slime mold cytochrome c oxidase: an example of enviromental influence on subunit composition of an eukariotic oxidase. Annals NY Acad Sci 550, 325-336.
96. Montecucco C, Papini E, Schiavo G, Rappuoli R and Tomasi M (1988) Studies on interaction of diphtheria toxin into biological membranes. In "Bacterial Protein Toxins" Zlb Bakt Suppl, Gustav Fisher Verlag, Stuttgart (D) 17, 287-294.
Edited Monographies
97. Albanese A, Cardoso F, Fujinaga Y, Jankovic J, Rummel A and Schiavo G (2018) Toxins 2017 conference in Madrid. Toxicon 147, 1.
98. Albanese A, Bigalke H, Foster K, Hallett M, Jankovic J, Montecucco C and Schiavo G (2009) Toxins 2008: Basic and Therapeutic Aspects of Botulinum and Tetanus Toxins. Toxicon 54, Issue 5.
99. Schiavo G and Chao MV Eds (2004) Axonal transport. J Neurobiol 58, Issue 2.
 
Selected publications
Sleigh JN, Dawes JM, West SJ, Wei N, Spaulding EL, Gómez-Martín A, Burgess RW, Cader MZ, Talbot K, Yang XL, Bennett DL and Schiavo G (2017) Sensory neuron fate is developmentally perturbed by Gars mutations causing human neuropathy. Proc Natl Acad Sci USA 114, E3324-E3333
Bercsenyi K, Schmieg N, Bryson JB, Wallace M, Caccin P, Golding M, Zanotti G, Greensmith L, Nischt R and Schiavo G (2014) Nidogens are therapeutic targets for the prevention of tetanus. Science 346 1118-23
Terenzio M, Golding M, Russell MRG, Wicher K, Rosewell I, Spencer-Dene B, Ish-Horowicz D and Schiavo G (2014) Bicaudal-D1 regulates the intracellular sorting and signalling of neurotrophin receptors. EMBO J, 33, 1582-98.
Cesca F, Yabe A, Spencer-Dene B, Scholz-Starke J, Medrihan L, Maden CH, Gerhardt H, Orriss IR, Baldelli P, Al-Qatari M, Koltzenburg M, Adams RH, Benfenati F and Schiavo G (2011) Kidins220/ARMS Mediates the Integration of the Neurotrophin and VEGF Pathways in Cardiovascular and Nervous System Development. Cell Death Differ doi: 10.1038/cdd.2011.141.
Bilsland L, Sahai E, Kelly G, Golding M, Greensmith L and Schiavo G (2010) Deficits in axonal transport precede ALS symptoms in vivo. Proc Natl Acad Sci U S A 107, 20523-20528.
Vilar M, Charalampopoulos I, Kenchappa RS, Simi A, Karaca E, Reversi A, Choi S, Bothwell M, Mingarro I, Friedman WJ, Schiavo G, Bastiaens PIH, Verveer PJ, Carter BD and Ibanez CF (2009) Activation of the p75 neurotrophin receptor through conformational rearrangement of disulphide-linked receptor dimers. Neuron 62, 72-83.
Deinhardt K, Salinas S, Verastegui C, Watson R, Worth D, Hanrahan S, Bucci C and Schiavo G (2006) Rab5 and Rab7 control endocytic sorting along the axonal retrograde transport pathway. Neuron 52, 293-305.
Deinhardt K, Berninghausen O, Willison HJ, Hopkins CR, Schiavo G (2006) A specific clathrin-dependent endocytic pathway coupled to axonal transport in motor neurons. J Cell Biol 174, 459-471
Rigoni M, Caccin P, Gschmeissner S, Koster G, Postle AD, Rossetto O, Schiavo G and Montecucco C (2005) Equivalent effects of snake PLA2 neurotoxins and lysophospholipid-fatty acid mixtures. Science 310, 1678-1680.
Hafezparast M, Klocke R, Ruhrberg C, Marquardt A, Ahmad-Annuar A, Bowen S, Lalli G, Witherden AS, Hummerich H, Nicholson S, Morgan PJ, Oozageer R, Priestley JV, Averill S, King VR, Ball S, Peters J, Toda T, Yamamoto A, Augustin M, Korthaus D, Wattler S, Wabnitz P, Dickneite C, Lampel S, Boehme F, Peraus G, Popp A, Rudelius M, Schlegel J, Fuchs H, Hrabe de Angelis M, Schiavo G, Shima DT, Russ AP, Stumm G, Martin JE and Fisher EMC (2003) Mutations in dynein link motor neuron degeneration to defects in retrograde transport. Science 300, 808-812.
Lalli G and Schiavo G (2002) Analysis of retrograde transport in motor neurons reveals common endocytic carriers for Tetanus Toxin and neurotrophin receptor p75NTR. J Cell Biol 156, 233-240.
Meunier FA, Feng ZP, Molgo J, Zamponi GW and Schiavo G (2002) Glycerotoxin from Glycera convoluta stimulates neurosecretion by up-regulating N-type Ca2+ channel activity. EMBO J 21, 6733-6743.
Schiavo G, Gmachl MJS, Stenbeck G, Sollner TH and Rothman JE (1995) A possible docking and fusion particle for synaptic transmission. Nature 378, 733-736.
Schiavo G, Benfenati F, Poulain B, Rossetto O, Polverino de Laureto P, Dasgupta BR and Montecucco C (1992) Tetanus and botulinum B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin. Nature 359, 832-835.
 
Manuscripts Submitted/Under Revision
Morais KLP1, Mozer Sciani J, Lamy MT, Duarte EL, Pasqualoto KFM,  Schmidt MCB, Maria Berra CM, Barbugiani Goldfeder M, Soares de Almeida ME, Pereira GJS, Pereira CDO, Machado-Santelli GM, Schiavo G and Chudzinski-Tavassi AM (2019) Modulation of intracellular sorting and phosphatidylserine surface exposure mediate the biological effects of the novel antitumor agent Amblyomin-X. Submitted.
Moretto E, Longatti A, Murru L, Chamma I, Sessa A, Zapata J, Hosy E, Sainlos M, Saint-Pol J, Rubinstein E, Choquet D, Broccoli V, Schiavo G, Thoumine O and Passafaro M (2019) TSPAN5 enriched microdomains provide a platform for dendritic spine maturation through neuroligin-1 clustering. Cell Rep, under revision.
Ohka S, Tan SH, Ishiyama E, Ogasawara K, Hanasaka T, Ishida K, Liu G, Choi-Sing CP, Hanaki K-I Schiavo G (2019) The uncoating environment is important for productive infection with EV71. Submitted.
Sebastián-Serrano A, Simón-García A, Belmonte A, Pose-Utrilla J, del Puerto A, García-Guerra L, Santos-Galindo M, Hernández IH, Schiavo G, Campanero MR, Lucas JJ and Iglesias T (2019) Differential regulation of Kidins220 isoforms in Huntington's disease. Submitted.
Sleigh JN, Rossor AM, Fellows AD, Tosolini AP and Schiavo G (2019) Axonal transport and neurological disease. Nat Rev Neurol. Submitted.
 
THE MOLECULAR NEUROPATHOBIOLOGY LABORATORY
Associated members
Pietro Fratta MD/ Clinician Scientist April 2015 - PRESENT
PhD Investigating deficits of axonal RNA metabolism and axonal signalling in amyotrophic lateral sclerosis
MRC Intermediate Clinician Scientist Fellowship
Nicol Birsa PhD Research fellow July 2015 - PRESENT
Investigating deficits of axonal RNA metabolism and axonal signalling in amyotrophic lateral sclerosis
Postdoctoral Fellows
James Sleigh PhD Research Fellow Oct 2014 - PRESENT
Dissecting Neuronal Specificity in Hereditary Neuropathy
Sir Henry Wellcome Postdoctoral Fellowship
Sergey Novoselov PhD Research fellow Oct 2014 - PRESENT
The mechanism controlling sorting and axonal retrograde transport in neurons
Andrew Tosolini PhD Research Fellow Jan 2016 - PRESENT
The mechanism controlling sorting and axonal retrograde transport in neurons
Sunaina Surana PhD Research Fellow Feb 2016 - PRESENT
The mechanism controlling sorting and axonal retrograde transport in neurons
Alex Rossor MD/ Research Fellow Apr 2016 - PRESENT
PhD Control of receptor trafficking as a therapeutic target in the inherited neuropathies 
Wellcome Trust Postdoctoral Training Fellowship for Clinicians
Oscar Marcelo Lazo PhD Research Fellow Apr 2016 - PRESENT
Neurotrophic signalling and the balance between retrograde signalling and autophagic flux in the axon CONICYT Becas-Chile Scholarship (Ch)

PhD Students
David Villaroel MSc Student Feb 2017 - PRESENT
Regulation of intracellular traffic by TBK1 and its relevance to Amyotrophic Lateral Sclerosis
MNDA PhD Fellowship

Ellie Rhymes PhD Student Sept 2017 - PRESENT
Does Ret inhibition rescue axonal transport deficits in the SOD1G93A mouse model of ALS?
MRC PhD Fellowship

Samantha De La-Rocque PhD Student Sept 2017 - PRESENT
Characterisation of interneuronal transfer of tau
MRC PhD Fellowship
 
Past Members
Postdoctoral Fellows
Judit Herreros PhD Research Fellow Jul 1997 - Feb 2001
Involvement of lipid rafts in neurospecific uptake of TeNT
HFSP Fellowship
Spanish Government Fellowship
Teresa Iglesias PhD Research Fellow Aug 1998 - Sep 1999
Cloning and characterisation of Kidins220
Frederic Meunier PhD Research Fellow Dec 1999 - Nov 2002
Toxin affecting neuroexocytosis
Travel Grant from British Council France
Giovanni Lesa PhD Research Fellow Oct 1999 - Oct 2003
Analysis of complex lipids in C. elegans
Wellcome Trust Travelling Fellowship
Carole Verastegui PhD Research Fellow Aug 2001 - Feb 2005
Biochemical analysis of TeNT receptors
Aurora Bracale PhD Research Fellow Nov 2002 - Feb 2005
Interacting partners of Kidins220
Short Term FEBS Fellowship
Alessandra Granata PhD Research Fellow Nov 2004 - Jun 2008
The cellular function(s) of TorsinA.
Wellcome Trust project grant
Sara Salinas PhD Research Fellow Jul 2004 - Sept 2008
Lipid raft and retrograde transport in motor neurons
EMBO Long Term Fellowship 
UCL Fellowship (6 months)
Olga Vites PhD Research Fellow Apr 2006 - Apr 2009
Role of rab7 effectors in retrograde transport
Veronika Neubrand PhD Research Fellow Nov 2005 - Oct 2009
Kidins220 regulates the activity of the Rho GEF Trio 
Fritz-Thyssen-Stiftung Fellowship
Lynsey Bilsland PhD Research Fellow Jan 2006 - Sep 2009
In vivo assay for axonal retrograde transport
Motor Neuron Disease Association project grant
Alessandra Reversi PhD Research Fellow Jan 2007 - Dec 2009
Regulation of Kidins220-kinesin interaction
Sunil Kappagantula PhD Research Fellow Jun 2010 - May 2011
Proteomics of axonal transport carriers
Olga Martins de Brito PhD Research Fellow Jan 2009 - May 2012
Regulation of Rab7 by RTK-dependent phosphorylation
EMBO Long Term Fellowship
Marie Curie Intra European Fellowship
Michael Parkinson PhD Research Fellow Aug 2010 - Sep 2013
Modulation of Rab GTPases along the axonal transport pathway
CRUK LRI PostDoctoral Fellowship
Solene Debaisieux PhD Research Fellow Oct 2011 - Nov 2015
Proteomics of axonal transport carriers
CRUK LRI PostDoctoral Fellowship
Marie Curie Intra European Fellowship
Alison Twelvetrees PhD Research Fellow Dec 2011 - Jan 2017 
Coordination of microtubule-dependent motors during axonal transport
Sir Henry Wellcome Postdoctoral Fellowship
From Dec 2011 to Jan 2016 at UPenn (E Holzbaur)

PhD Students
Shona L. Osborne PhD Student Oct 1997 - Sep 2001
"PtdIns(4,5)P2: An essential lipid involved in membrane dynamics and nuclear physiology"
Giovanna Lalli PhD Student Mar 1998 - Feb 2002
PhD Research Fellow Mar 2002 - Dec 2002
PhD Thesis "The binding fragment of TeNT: a probe to study neuronal endocytosis and retrograde transport"
Recipient of the "Guido Pontecorvo" Prize for best PhD Thesis
Gerald Hammond PhD Student Oct 2001 - Feb 2006
PhD Thesis "The role of phosphoinositides in mast cell exocytosis"
Stephanie Bohnert Diploma Student Sep 2001- Apr 2002
PhD Student Oct 2002 - Jul 2006
PhD Thesis "pH analysis of endocytic carriers in motor neurons"
Katrin Deinhardt PhD Student Oct 2002 - Nov 2005
PhD Research Fellow Nov 2005 - Nov 2006
PhD Thesis "The endocytic pathway of tetanus toxin in motor neurons"
Fabrizia Cesca PhD Student Oct 2003 - Sep 2007
PhD Research Fellow Sep 2007 - Jul 2008
PhD Thesis "Function of Kidins220 in health and disease"
Marco Terenzio PhD Student Sep 2006 - Dec 2010
PhD Visiting Fellow Jun 2012 - Oct 2012
PhD Thesis "A novel RNAi screen for neurotrophin receptor internalisation and trafficking in motor neurons"
FP6 Marie Curie RTN PhD Fellowship
Guillermo Menendez PhD Student Aug 2006 - Jul 2010
PhD Research Fellow Aug 2010 - Dec 2010
PhD Thesis "Microfluidics in the study of vesicular transport in neurons"
Chemical Biology Centre studentship
Anna Wade PhD Student Sep 2007 - Dec 2010 
PhD Thesis "A novel role for activated Leukocyte cell adhesion molecule (ALCAM) in neurotrophin signalling in neurons"
Wellcome Trust PhD Prize Studentship
Arisa Yabe PhD Student Oct 2007 - Dec 2011
PhD Thesis "In vivo functional analysis of Kidins220"
Overseas Research Scholarship, UCL
Martin Wallace PhD Student Oct 2010 - Sep 2014
PhD Thesis "Functional screens in human motor neurons"
MRC Industrial CASE PhD Studentship
Kinga Bercsenyi PhD Student Oct 2010 - Jan 2015 PhD Thesis "Identification of the TeNT receptor complex" 
Katherine Gibbs PhD Student Oct 2011 - Sep 2015
PhD Thesis "Modifying axonal transport as a therapeutic strategy for ALS"
BBSRC Industrial CASE PhD Studentship
Nathalie Schmieg PhD Student Oct 2011 - Jan 2016
Trafficking of growth factor receptors in Kidins220-/- neurons
CRUK LRI PhD Fellowship
Marta Budzinska PhD Student Oct 2014 - PRESENT Mechanisms controlling the axonal retrograde transport pathway 
BBSRC Industrial CASE PhD Studentship
Alexander Fellow PhD Student Sep 2014 - PRESENT
Deficits in axonal transport as a target for pharmacological intervention in Amyotrophic lateral sclerosis
Leonard Wolfson PhD Studentship
Ione Meyer PhD Student Sep 2014 - PRESENT
Basal lamina components in axonal transport and transcytosis
MRC Centre for Neuromuscular Diseases PhD Studentship

Visiting Research Fellows
Carles Gil Giro' PhD Research Fellow Mar 2001 - Aug 2001
TeNT and neurotrophin complexes in brain Oct 2003 - Jan 2004
Spanish visiting Fellowship (E) Feb 2005 - Mar 2005
Laura Restani PhD Research Fellow Sep 2008 - Feb 2009
Retrograde transport of botulinum neurotoxins
Silvia Mion Prize, University of Verona (I) 
Maria Manich Undergraduate student Jul 2008 - Aug 2009
Retrograde transport of botulinum neurotoxins
Fongecif travel fellowship (F)
Edoardo Moretto MSc Student Apr 2011 - Sep 2011
A quantitative proteomic approach to dystonia
Studentships: Collegio Superiore, University of Bologna (I);
Alma Mater Studiorum, University of Bologna (I); 
Physical Sciences Faculty; University of Bologna (I)
Francesco Giribaldi PhD Student Jan 2011 - Dec 2011
Jul 2012 - Sep 2012
BoNT/A and E undergo retrograde transport in motor neurons"
Studentship; University of Genova (I)

Pilar González Cabo PhD Mar 2012 - Aug 2012
Differentiation of mouse ES cells into sensory neurons
Jose Castillejo program, Spanish Government Fellowship (E)

Scientific Officers
Felicia A. Hunte MSc Scientific Officer Oct 2001 - Jul 2003 
Kidins220 as marker for malignant astrocytomas
Daniel Worth PhD Scientific Officer Jan 2006 - Jul 2006
Claire L. Thomas MSc Senior Scientific Officer Jan 1997 - Aug 2013
Kidins220/ARMS functions in health and disease
Matthew Golding PhD Principal Scientific Officer Jan 2003 - Sep 2013
Mutations in cytoplasmic dynein


 

 
 



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