Istituto Veneto di Scienze, Lettere ed Arti - Testata per la stampa
Giampietro Schiavo

Giampietro Schiavo

Professore di Neurobiologia cellulare all'University College of London

- s.s. eletto il 23 marzo 2019

MSc in Biological Sciences, University of Padua, Italy (1992)
MSc in Chemistry and Pharmaceutical Technology, University of Padua, Italy (1988)

2019-present Deputy Director, UCL Queen Square Institute of Neurology (UCL-QS-ION), UK 
2018-present Associate member, The Francis Crick Institute, UK 
2017-present UK Dementia Research Institute at UCL Professorship
2015-present Deputy Head, Department of Neuromuscular Diseases, UCL-QS-ION, UK
2014-present Lead Academic Scientist, ARUK UCL Drug Discovery Institute, UCL, UK
2013-present Professor of Cellular Neurobiology, UCL Queen Square Institute of Neurology, UCL, UK
2007-2013 Honorary Professor, Dept of Cell & Developmental Biology, UCL, UK
2003-2013 Senior Group Leader (tenured), Cancer Research UK London Research Institute, UK
2003-2006 Honorary Reader, Dept of Biochemistry and Molecular Biology, UCL, UK
1997-2003 Honorary Senior Research Fellow, Dept of Biochemistry and Molecular Biology, UCL, UK
1996-2002 Group Leader, Cancer Research UK London Research Institute, UK
1992-1995 Senior Researcher, Dept of Biomedical Sciences, University of Padua, Italy
1983-1991 Research Associate, Institute of General Pathology, University of Padua, Italy

2017 UK Dementia Research Institute at UCL Professorship 
2009 CaRiPaRo Foundation Visiting Professorship at the Scuola Galileiana di Studi Superiori, University of Padua (I)
1994 Long term European Molecular Biology Organization fellowship (Dr JE Rothman, Memorial Sloan-Kettering Cancer Center, New York (NY)

2002 Giovanni Armenise-Harvard Foundation Career Development Award
1995 International Society for Neurochemistry (ISN) Young Scientist Award
1993 Award of the Italian National Academy of Sciences "Dott Giuseppe Borgia"
1988 Award for the best student of Chemistry and Pharmaceutical Technology, University of Padua (I)

Membership of Professional Bodies
2019-present Foreign Fellow, Istituto Veneto di Scienze, Lettere ed Arti (IVSLA)
2014-present Fellow, Royal Society of Biology (FRSB)
2011-present Fellow, Academy of Medical Sciences (FMedSci)
2010-present Member, European Molecular Biology Organization (EMBO)

Membership of Learned Societies
2015-present Member, British Society for Cell Biology
1994-present Member, International Society for Neurochemistry 
1997-2010 Member, Biochemical Society
1993-1997 Member, Italian Society of Biophysics and Molecular Biology (SIBBM)

Editorial Boards
2016-present Editorial Board, Matters
2008-present Review Editor, Frontiers in Neuroengineering
2008-present Editorial Board, Protein Journal
2007-present Editor, Journal of Cell Science (Neuroscience)
2009-2016 Academic Editor, PLoS Biology
2002-2015 Editorial Board, Traffic
2009-2015 Editorial Board, Cell Death & Disease
2006-2009 Editorial Board, Neurotoxicity Research 
2005-2009 Deputy Chief Editor, Journal of Neurochemistry 
2002-2005 Editor, Journal of Neurochemistry

Advisory Boards/ Board of Directors
2019-present Advisory Board, Fastox Pharma, Lausanne (CH)
2019-present Scientific Advisory Board, IRCCS Istituto Neurologico Carlo Besta, Milan (I)
2019-present International Neurotoxin Association (INA), Past President
2017-2019 International Neurotoxin Association (INA), President 
2018 Scientific Advisory Board, "Synaptopathies Wellcome Collaborative Award"
2015-2018 Advisory Board, University of Milan (I).
2015-2017 International Neurotoxin Association (INA), President elect
2010-2017 International Neurotoxin Association (INA), Board of Directors
2013-2015 International Neurotoxin Association (INA), Treasurer
2007-2010 The Neurotoxin Institute Steering Committee, New York (NY)
2006-2013 Research Board of the Chemical Biology Centre, London (UK)
2005-2006 Advisory Board of the Chemical Biology Centre, London (UK)

Award & Selection Committees
2020-2021 TOXIN2021 Basic Science selection committee
2017 Journal of Cell Science - Company of Biology Travelling Fellowship selection chair
2017 ETOX18 selection committee
2016 Institute of Neurology Queen Square Prize selection panel
2015 9th Basic and Therapeutic Aspects of Botulinum and Tetanus Toxins selection committee
2013 EMBO Meeting selection committee
2013 ETOX16 selection committee
2012 8th Basic and Therapeutic Aspects of Botulinum and Tetanus Toxins selection committee
2009-2011 Peter and Patricia Gruber International Research Award in Neuroscience committee
2010 Journal of Cell Science - Company of Biology Travelling Fellowship selection chair

Scientific Institute Evaluation/Recruitment Committees
2019 Tenure Committee, Laboratory of Molecular Biology, Cambridge (UK)
2019 Mitochondria Biology Strategy, MRC, London (UK)
2018 Institut Pasteur, Department of Cell Biology and Infection, Paris (F)
2018 MRC Cognition and Brain Sciences Unit, Cambridge (UK) (Chair)
2018 Centro de Biologia Molecular Severo Ochoa (CBMSO), Madrid (E)
2015-2017 Institut Pasteur Recruitment Committee, Paris (F)
2014-2016 Evaluation and Steering Committee, Butantan Institute, Sao Paulo (Br)
2015 Laboratory of Molecular Biology (Neuroscience Division), Cambridge (UK)
2014 Institut Curie recruitment committee, Paris (F)
2014 Maurice Wohl Institute recruitment committee, King's College London (UK)
2013 Department of Health Science (DISS), University of Milan (I)
2013 Promotion Committee, Max F. Perutz Laboratories, Vienna (AT)
2009 Institut Curie/Inserm Unit "Signalisation, neurobiologie et cancer", Paris (F)
2009 Institut Pasteur, Department of Cell Biology and Infection, Paris (F)
To date I have published 166 research papers and 101 reviews in prestigious scientific journals, which have been highly cited (>23,050 total citations, >1,000 citations per year in 2011-2018; e.g. Schiavo et al. (1992) Nature 359:832, 1,746 citations; Schiavo et al. (2000) Physiol Rev 80:717, 1,282 citations; Hafezparast et al. (2003) Science 300:808, 740 citations). 

My h-index is 79 and i10-index 204 (44 and 136 since 2014; source: Google Scholar).

Manuscripts preprints
Humphrey J, Birsa N, Milioto C, Robaldo D, Eberle A, Kräuchi R, Bentham M, Ule A, Jarvis S, Bodo C, Garone MG, Devoy A, Rosa A, Bozzoni I, Fisher EMC, Ruepp M-C, Mühlemann O, Schiavo G, Isaacs A, Plagnol V and Fratta P (2019) FUS ALS-causative mutations impact FUS autoregulation and the processing of RNA-binding proteins through intron retention. bioRxiv. doi: A, Morishita S, Kjaer S, Fukuda M, Schiavo G and Nakamura T (2018) Comparable affinity of RabGDIα to GTP- and GDP-bound forms of Rab7 supports a four-state transition model for Rab7 subcellular localization. bioRxiv. doi: JN, Tosolini AP, Gordon D, Devoy A, Fratta P, Fisher EMC, Talbot K and Schiavo G (2018) ALS mice carrying pathological mutant TDP-43, but not mutant FUS, display axonal transport defects in vivo. bioRxiv. doi:
Research Papers
1. Moretto E, Longatti A, Murru L, Chamma I, Sessa A, Zapata J, Hosy E, Sainlos M, Saint-Pol J, Rubinstein E, Choquet D, Broccoli V, Schiavo G, Thoumine O and Passafaro M (2019) TSPAN5 enriched microdomains provide a platform for dendritic spine maturation through neuroligin-1 clustering. Cell Rep, in press.
2. Sebastián-Serrano A, Simón-García A, Belmonte A, Pose-Utrilla J, del Puerto A, García-Guerra L, Santos-Galindo M, Hernández IH, Schiavo G, Campanero MR, Lucas JJ and Iglesias T (2019) Differential regulation of Kidins220 isoforms in Huntington's disease. Brain Pathol, in press. 
3. Sleigh JN, Tosolini AP and Schiavo G (2019) In vivo imaging of anterograde and retrograde axonal transport in rodent peripheral nerves. Methods Mol Biol, in press.
4. Kalinski AL, Kar AN, Craver J, Tosolini AP, Sleigh JN, Lee SJ, Hawthorne A, Brito-Vargas P, Miller-Randolph S, Passino R, Shi L, Wong VSC, Picci C, Smith DS, Bassell GJ, Willis DE, Havton LA, Schiavo G, Giger RJ, Langley B and Twiss JL (2019) Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition. J Cell Biol 218, 1871-90.
5. Vargas JNS, Wang C, Bunker E, Hao L, Maric D, Schiavo G, Randow F and Youle RJ (2019) Spatiotemporal control of ULK1 activation 1 by NDP52 and TBK1 during selective autophagy. Mol Cell 74, 1-16.
6. Goto-Silva L, McShane MP, Salinas S, Kalaidzidis Y, Schiavo G and Zerial M (2019) Retrograde transport of Akt by a neuronal Rab5-APPL1 signaling endosome. Sci Rep 9, 2433.
7. Shorrock HK, van der Hoorn D, Boyd PJ, Hurtado ML, Lamont DJ, Wirth B, Sleigh JN, Schiavo G, Wishart TM, Groen EJN and Gillingwater TH (2018) UBA1/GARS-dependent pathways drive sensory-motor connectivity defects in spinal muscular atrophy. Brain 141, 2878-94.
8. Clark AJ, Menendez G, AlQatari M, Patel N, Årstad E, Schiavo G and Koltzenburg M (2018) Functional imaging in microfluidic chambers reveal sensory neuron sensitivity is differentially regulated between neuronal regions. Pain 159, 1413-25.
9. Gibbs KL, Kalmar B, Rhymes ER, Fellows AD, Ahmed M, Whiting P, Davies C, Greensmith L and Schiavo G (2018) Inhibiting p38 MAPK alpha rescues axonal retrograde transport defects in a mouse model of ALS. Cell Death Dis 9, 596.
10. Tyzack GE, Hall C, Sibley C, Cymes T, Forostyak S, Meyer IFG, Schiavo G, Zhang S-C, Gibbons G, Newcombe J, Patani R and Lakatos A (2017) A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models. Nat Commun 8, 1164.
11. Sleigh JN, Gomez-Martin A, Wei N, Yang XL and Schiavo G (2017) Neuropilin 1 sequestration by neuropathogenic mutant glycyl-tRNA synthetase is permissive to vascular homeostasis. Sci Rep 7, 9216.
12. Kalmar B, Innes A, Wanisch K, Kolaszynska AK, Amelie Pandraud A, Kelly G, Abramov A, Reilly M, Schiavo G and Greensmith L (2017) Mitochondrial dysfunction leading to axonal transport deficits in mutant Hsp27 induced Charcot Marie Tooth Disease. Hum Mol Genet. 26, 3313-3326.
13. Sleigh JN, Dawes JM, West SJ, Wei N, Spaulding EL, Gómez-Martín A, Burgess RW, Cader MZ, Talbot K, Yang XL, Bennett DL and Schiavo G (2017) Sensory neuron fate is developmentally perturbed by Gars mutations causing human neuropathy. Proc Natl Acad Sci USA 114, E3324-E3333.
See: Richter S, Helm C, Meunier FA, Hering L, Campbell LI, Drukewitz SH, Undheim EAB, Jenner RA, Schiavo G and Bleidorn C (2017) Comparative analyses of glycerotoxin expression unveil a novel structural organization of the bloodworm venom system. BMC Evol Biol 17, 64.
15. Charlier CM, Debaisieux S, Foret C, Thouard A, Schiavo G, Gonzalez-Dunia D and Malnou CE (2016) Neuronal retrograde transport of Borna disease virus occurs in signaling endosomes. J Gen Virol. 97, 3215-3224.
16. Zussy C, Loustalot F, Junyent F, Gardoni F, Bories C, Desarmenien MG, Valero J, Bernex F, Henaff D, Bayo-Puxan N, Chen J-W, Lonjon N, De Koninck Y, Malva J, Bergelson JMB, Di Luca M, Schiavo G, Salinas S and Kremer EJ (2016) Coxsackievirus adenovirus receptor loss impairs adult neurogenesis, synapse content and hippocampus plasticity. J Neurosci 36, 9558-71.
17. Sleigh JN and Schiavo G (2016) Older but not slower: aging does not alter axonal transport dynamics of signalling endosomes in vivo. Matters 10.19185/matters.201605000018.
18. Twelvetrees AE, Pernigo S, Sanger A, Schiavo G, Steiner RA, Dodding MP, Holzbaur EL (2016) The dynamic localization of cytoplasmic dynein in neurons is driven by kinesin-1. Neuron 90, 1000-15.
19. Ahmed M, Machado P, Miller A, Spicer C, Herbelin L, He J, Noel J, Wang Y, McVey AL, Pasnoor M, Gallagher P, Statland J, Lu C-H, Kalmar B, Brady S, Sethi H, Samandouras G, Parton M, Holton JL, Weston A, Collinson L, Taylor JP, Schiavo G, Hanna MG, Barohn RJ, Dimachkie MM, Greensmith L (2016) Targeting protein homeostasis in sporadic inclusion body myositis. Sci Transl Med 8, 331ra41.
20. Sleigh JN, Weir GA and Schiavo G (2016) A simple, step-by-step dissection protocol for the rapid isolation of mouse dorsal root ganglia. BMC Res Notes 9, 82.
21. Debaisieux S, Encheva V, Chakravarty P, Snijders AP and Schiavo G (2016) Analysis of signaling endosome composition and dynamics using SILAC in embryonic stem cell-derived motor neurons. Mol Cell Proteomics 15, 542-57.
22. Gibbs K, Kalmar B, Sleigh JN, Greensmith L and Schiavo G (2016) In vivo imaging of axonal transport in murine motor and sensory neurons. J Neurosci Meth 257, 26-33.
23. Simão D, Pinto C, Fernandes P, Peddie CJ, Piersanti C, Collinson LM, Salinas S, Saggio I, Schiavo G, Kremer EJ, Brito C and Alves PM (2016) Evaluation of helper-dependent 1 canine adenovirus vectors in a 3D human CNS model. Gene Ther 23, 86-94.
24. Yasuda S, Morishita S, Fujita A, Nanao T, Wada N, Waguri S, Schiavo G, Fukuda M and Nakamura T (2016) Mon1-Ccz1 activates Rab7 only on the late endosome and dissociates from the lysosome in mammalian cells. J Cell Sci 29, 329-40. 
25. Schmieg N, Thomas C, Yabe A, Lynch DS, Iglesias T, Chakravarty P and Schiavo G (2015) Novel Kidins220/ARMS splice isoforms: potential specific regulators of neuronal and cardiovascular development. PLoS One 10, e0129944.
26. Simão D, Pinto C, Piersanti S, Weston A, Peddie CJ, Bastos AE, Licursi V, Schwarz SC, Collinson LM, Salinas S, Serra M, Teixeira AP, Saggio I, Lima PA, Kremer EJ, Schiavo G, Brito C and Alves PM (2014) Modeling human neural functionality in vitro: 3D culture for dopaminergic differentiation. Tissue Eng Part A 21, 654-68.
27. Bercsenyi K, Schmieg N, Bryson JB, Wallace M, Caccin P, Golding M, Zanotti G, Greensmith L, Nischt R and Schiavo G (2014) Nidogens are therapeutic targets for the prevention of tetanus. Science 346, 1118-23.
See: Wang Y, Chakravarty P, Ranes M, Kelly GP, Brooks PJ, Neilan E, Stewart A, Schiavo G and Svejstrup JQ (2014) Dysregulation of gene expression as the cause of Cockayne syndrome neurologic disease. Proc Natl Acad Sci U S A 111, 14454-9.
29. Terenzio M, Golding M, Russell MRG, Wicher K, Rosewell I, Spencer-Dene B, Ish-Horowicz D and Schiavo G (2014) Bicaudal-D1 regulates the intracellular sorting and signalling of neurotrophin receptors. EMBO J 33, 1582-98. 
30. Terenzio M, Golding M and Schiavo G (2014) siRNA screen of ES cell-derived motor neurons identifies novel regulators of tetanus toxin and neurotrophin receptor trafficking. Frontiers Cell Neurobiol 8, 140.
31. Hislop JN, Islam TA, Eleftheriadou I, Carpentier DCJ, Trabalza A, Parkinson M, Schiavo G and Mazarakis ND (2014) Rabies virus envelope glycoprotein targets lentiviral vectors to the axonal retrograde pathway in motor neurons. J Biol Chem 289, 16148-63.
32. Garrett CA, Barri M, Kuta A, Soura V, Deng W, Fisher EMC, Schiavo G and Hafezparast M (2014) DYNC1H1 mutation alters transport kinetics and ERK1/2-cFos signalling in a mouse model of distal spinal muscular atrophy. Brain 137, 1883-93.
33. Salinas S, Zussy C, Loustalot F, Henaff D, Menendez G, Morton PE, Parsons M, Schiavo G and Kremer EJ (2014) Disruption of the coxsackievirus and adenovirus receptor-homodimeric interaction triggers lipid microdomain- and dynamin-dependent endocytosis and lysosomal targeting J Biol Chem 289, 680-95.
34. Ferrari E, Gu C, Niranjan D, Restani L, Rasetti-Escargueil C, ObaraI I, Geranton SM, Arsenault J, Goetze TA, Harper CB, Nguyen TH, Maywood E, O'Brien J, Schiavo G, Wheeler DW, Meunier F, Hastings M, Edwardson JM, Sesardic D, Caleo M, Hunt SP and Davletov BA (2013) A synthetic self-assembling clostridial chimera for modulation of sensory functions. Bioconjug Chem 24, 1750-9.
35. Goold R, McKinnon C, Rabbanian S, Collinge J, Schiavo G and Tabrizi SJ (2013) Trafficking and degradation kinetics of newly formed PrPSc in the first minutes following initial prion conversion. J Cell Sci 126,3552-62.
36. Cogli C, Progida C, Thomas CL, Spencer-Dene B, Donno C, Schiavo G and Bucci C (2013) Charcot-Marie-Tooth type 2B disease-causing RAB7A mutant proteins show altered interaction with the neuronal intermediate filament peripherin. Acta Neuropathol 125, 257-72.
37. Restani L, Giribaldi F, Manich M, Bercsenyi K, Menendez G, Rossetto O, Caleo M and Schiavo G (2012) Botulinum neurotoxins A and E undergo retrograde axonal transport in primary motor neurons. PLoS Pathog 8, e1003087.
38. Rishal I, Kam N, Shinder V, Fisher EMC, Schiavo G and Fainzilber M (2012) Motor driven intracellular length sensing in neurons. Cell Rep 1, 1-9.
39. Scholz-Starke J, Cesca F, Schiavo G, Benfenati F and Baldelli P (2012) Kidins220/ARMS is a Novel Modulator of Short-term Synaptic Plasticity in Hippocampal GABAergic Neurons. PLoS ONE 4, e35785.
40. Wade A, Kalmar B, Terenzio M, Garin J, Greensmith L and Schiavo G (2012) Activated leukocyte cell adhesion molecule (ALCAM) modulates neurotrophin signaling. J Neurochem, 21, 575-86.
41. Cesca F, Yabe A, Spencer-Dene B, Scholz-Starke J, Medrihan L, Maden CH, Gerhardt H, Orriss IR, Baldelli P, Al-Qatari M, Koltzenburg M, Adams RH, Benfenati F and Schiavo G (2012) Kidins220/ARMS Mediates the Integration of the Neurotrophin and VEGF Pathways in Cardiovascular and Nervous System Development. Cell Death Differ 19, 194-208.
42. Cesca F, Yabe A, Spencer-Dene B, Arrigoni A, Al-Qatari M, Henderson D, Koltzenburg M, Benfenati F and Schiavo G (2011) Kidins220/ARMS is an Essential Modulator of Cardiovascular and Nervous System Development. Cell Death Dis 2:e226.
43. Ferrari E, Maywood E, Caleo M, Restani L, Schiavo G, Pirazzini M, Rossetto O, Montecucco C, Hastings M, Niranjan D and Davletov B (2011) Re-assembled botulinum neurotoxin inhibits CNS functions without systemic toxicity. Toxins 3, 345-55.
44. Sannerud R, Declerck I, Peric A, Raemaekers T, Menendez G, Zhou L, Baert V, Coen K, Munck S, De Strooper B, Schiavo G and Annaert W (2011) ARF6 controls APP processing by mediating the endosomal sorting of BACE1. Proc Natl Acad Sci U S A 108, E559-68.
45. Goold R, Rabbanian S, Sutton L, Andre R, Arora P, Moonga J, Clarke AR, Schiavo G, Jat P, Collinge J and Tabrizi SJ (2011) Rapid cell surface prion protein conversion revealed using a novel cell system. Nat Commun 2, 281.
46. Malik B, Nirmalananthan N, Bilsland LG, La Spada AR, Hanna MG, Schiavo G, Gallo J-M and Greensmith L (2011) Absence of disturbed axonal transport in spinal and bulbar muscular atrophy. Hum Mol Genet 20, 1776-1786.
47. Granata A, Haucke V, Schiavo G* and Warner TT* (2011) CSN complex controls the stability of selected synaptic proteins via a torsinA-dependent process. EMBO J 30, 181-193. *Equal contribution.
48. Bilsland L, Sahai E, Kelly G, Golding M, Greensmith L and Schiavo G (2010) Deficits in axonal transport precede ALS symptoms in vivo. Proc Natl Acad Sci U S A 107, 20523-20528.
49. Neubrand NE, Thomas C, Schmidt S, Debant A and Schiavo G (2010) Kidins220/ARMS regulates Rac1 dependent neurite outgrowth via a direct interaction with the RhoGEF Trio. J Cell Sci 123, 2111-2123.
50. Meunier FA, Nguyen TH, Colasante C, Luo F, Sullivan RKP, Lavidis NA, Molgo J, Meriney SD and Schiavo G (2010) Sustained synaptic vesicle recycling by bulk endocytosis contributes to maintaining the high-rate neurotransmitter release stimulated by Glycerotoxin. J Cell Sci 123, 1131-1140.
51. Stevens JC, Chia R, Hendricks WT, Bros-Facer V, van Minnen J, Martin JE, Jackson GS, Greensmith L, Schiavo G and Fisher EMC (2010) Modification of superoxide dismutase 1 (SOD1) properties by a GFP tag - implications for research into amyotrophic lateral sclerosis. PLoS ONE 5, e9541.
52. Pichlmair A, Schulz O, Tan C-P, Rehwinkel J, Kato H, Takeuchi O, Akira S, Way M, Schiavo G and Reis e Sousa C (2009) Activation of MDA5 requires higher order RNA structures generated during virus infection. J Virol 83, 10761-10769.
53. Vilar M, Charalampopoulos I, Kenchappa RS, Reversi A, Applequist J, Karaca E, Simi A, Spuch C, Choi S, Friedman WJ, Ericson J, Schiavo G, Carter BD and Ibanez CF (2009) Ligand-independent signaling by genetically-crosslinked dimers of the p75 neurotrophin receptor. J Cell Sci 122, 3351-3357.
54. Hammond GRV, Schiavo G and Irvine RF (2009) Novel immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4P and PtdIns(4,5)P2. Biochem J 422, 23-35.
55. Rinaldi S, Brennan KM, Goodyear CS, O'Leary CO, Schiavo G, Crocker PR and Willison HJ. (2009) Analysis of lectin binding to glycolipid complexes using combinatorial microarrays. Glycobiology 19, 789-796.
56. Salinas S, Bilsland L, Henaff D, Weston AE, Keriel A, Schiavo G* and Kremer EJ* (2009) CAR-dependent vesicular transport of an adenovirus in primary motor neurons. PloS Pathogens 5, e1000442. *Equal contribution.
57. Ohka S, Sakai M, Bohnert S, Igarashi H, Deinhardt K, Schiavo G and Nomoto A. (2009) Receptor-dependent and -independent axonal retrograde transport of poliovirus in motor neurons. J Virol 83, 4995-5004.
58. Vilar M, Charalampopoulos I, Kenchappa RS, Simi A, Karaca E, Reversi A, Choi S, Bothwell M, Mingarro I, Friedman WJ, Schiavo G, Bastiaens PIH, Verveer PJ, Carter BD and Ibanez CF (2009) Activation of the p75 neurotrophin receptor through conformational rearrangement of disulphide-linked receptor dimers. Neuron 62, 72-83.
59. Semerdjieva S, Shortt B, Maxwell E, Sukhdeep S, Fonarev P, Hansen J, Schiavo G, Grant BD and Smythe E. (2008) Coordinated regulation of AP2 uncoating from clathrin-coated vesicles by Rab5 and hRME-6. J Cell Biol 183, 499-511.
60. Granata A, Watson R, Collinson LM, Schiavo G* and Warner TT*. (2008) The dystonia-associated protein torsinA modulates synaptic vesicles recycling. J Biol Chem 283, 7568-7579. *Equal contribution.
61. Fasano C, Campana V, Kelly G, Schulze A, Schiavo G and Zurzolo C (2008) Gene expression profile of quinacrine-cured prion-infected mouse neuronal cells. J Neurochem 105, 239-250.
62. Magnani E, Fan J, Gasparini L, Golding M, Williams M, Schiavo G, Goedert M, Amos LA and Spillantini MG (2007) Interaction of tau protein with the dynactin complex. EMBO J 26, 4546-4554.
63. Deinhardt K, Berninghausen O, Hopkins CR and Schiavo G (2007) Neurotrophins redirect p75NTR from a clathrin-independent to a clathrin-dependent endocytic pathway coupled to axonal transport. Traffic 8, 1736-1749
64. Kasperaviciute D, Weale ME, Shianna KV, Banks GT, Simpson CL, Hansen VK, Turner MR, Shaw CE, Al-Chalabi A, Pall HS, Goodall EF, Morrison KE, Orrell RW, Beck M, Jablonka S, Sendtner M, Brockington A, Ince P, Hartley J, Nixon H, Shaw P, Schiavo G, Wood NW, Goldstein DB and Fisher EM (2007) Large-scale pathways based association study in amyotrophic lateral sclerosis. Brain 30, 2292-2301.
65. Bowen S, Ateh DD, Deinhardt K, Bird MM, Price KM, Baker CS, Robson JC, Swash M, Shamsuddin W, Kawar S, El-Tawil T, Roos J, Hoyle A, Nickols CD, Knowles CK, Pullen AH, Luthert PJ, Weller RO, Hafezparast M, Franklin RJM, Revesz T, King RHM, Berninghausen O, Fisher EMC, Schiavo G and Martin JE (2007) The phagocytic capacity of neurons. Eur J Neurosci 25, 2947-2955.
66. Rigoni M, Pizzo P, Schiavo G, Weston AE, Zatti G, Caccin P, Rossetto O, Pozzan T and Montecucco M (2007) Calcium influx and mitochondrial alterations at synapses exposed to snake neurotoxins or their phospholipid hydrolysis products. J Biol Chem 282, 11238-11245.
67. Bracale A, Cesca F, Neubrand VE, Newsome TP, Way M and Schiavo G (2007) Kidins220/ARMS is transported by a kinesin-1 based mechanism likely to be involved in neuronal differentiation. Mol Biol Cell 18, 142-152.
68. Deinhardt K, Salinas S, Verastegui C, Watson R, Worth D, Hanrahan S, Bucci C and Schiavo G (2006) Rab5 and Rab7 control endocytic sorting along the axonal retrograde transport pathway. Neuron 52, 293-305.
69. Deinhardt K, Berninghausen O, Willison HJ, Hopkins CR and Schiavo G (2006) A specific clathrin-dependent endocytic pathway coupled to axonal transport in motor neurons. J Cell Biol 174, 459-471.
70. Schenning M, Proctor DT, Ragnarsson L, Barbier J, Lavidis NA, Molgó JJ, Zamponi GW, Schiavo G and Meunier FA (2006) Glycerotoxin stimulates neurotransmitter release from N-type Ca2+ channel expressing neurons. J Neurochem 98, 894-904.
71. Hammond GRV, Dove SK, Nicol A, Pinxteren JA, Zicha D and Schiavo G (2006) Hydrolysis of phosphatidylinositol (4,5)-bisphosphate is required for exocytosis from mast cells. J Cell Sci 119, 2084-2094.
72. Rigoni M, Caccin P, Gschmeissner S, Koster G, Postle AD, Rossetto O, Schiavo G and Montecucco C (2005) Equivalent effects of snake PLA2 neurotoxins and lysophospholipid-fatty acid mixtures. Science 310, 1678-1680.
73. Bohnert S and Schiavo G (2005) Tetanus toxin is transported in a novel neuronal compartment characterized by a specialized pH regulation. J Biol Chem 280, 42336-42344.
74. Salinas S, Carazo-Salas RE, Proukakis C, Cooper JM, Weston AE, Schiavo G and Warner TT (2005) Human spastin has multiple microtubule-related functions. J Neurochem 95, 1411-1420.
75. Meunier FA, Osborne SL, Hammond GR, Cooke FT, Parker PJ, Domin J and Schiavo G (2005) Phosphatidylinositol 3-kinase C2 is essential for ATP-dependent priming of neurosecretory granule exocytosis. Mol Biol Cell 16, 4841-4851.
76. Achilli F, Boyle S, Kieran D, Chia R, Hafezparast M, Martin JE, Schiavo G, Greensmith L, Bickmore W and Fisher EMC (2005) The SOD1 transgene in the G93A mouse model of amyotrophic lateral sclerosis lies on distal mouse chromosome 12. Amyotroph Lateral Scler Other Motor Neuron Disord 6, 111-114.
77. Kieran D, Hafezparast M, Bohnert S, Dick JR, Martin J, Schiavo G, Fisher EMC and Greensmith L (2005) A mutation in dynein rescues axonal transport defects and extends the life span of ALS mice. J Cell Biol 169, 561-567.
78. Parsons M, Monypenny J, Ameer-Beg SM, Millard TH, Machesky LM, Peter M, Keppler MD, Schiavo G, Watson R, Chernoff J, Zicha D, Vojnovic B and Ng T (2005) Spatially distinct binding of Cdc42 to PAK1 and N-WASP in breast carcinoma cells. Mol Cell Biol 25, 1680-1695.
79. Misbahuddin A, Placzek MR, Taanman JW, Gschmeissner S, Schiavo G, Cooper JM and Warner TT (2005) Mutant torsinA, which causes early-onset primary torsion dystonia, is redistributed to membranous structures enriched in vesicular monoamine transporter in cultured human SH-SY5Y cells. Mov Disord 20, 432-440.
80. Rigoni M, Schiavo G, Weston AE, Caccin P, Allegrini F, Pennuto M, Valtorta F, Montecucco C and Rossetto O (2004) Snake presynaptic neurotoxins with phospholipase A2 activity induce swelling of synaptic boutons and exocytosis of synaptic vesicles. J Cell Sci, 117 3561-3570.
81. Lesa GM, Palfreyman M, Hall DH, Clandinin MT, Rudolph C, Jorgensen EM and Schiavo G (2003) Long chain polyunsaturated fatty acids are required for efficient neurotransmission in C. elegans. J Cell Sci 116, 4965-4975.
82. Lalli G, Gschmeissner S and Schiavo G (2003) Myosin Va and microtubule-based motors are required for fast axonal retrograde transport of tetanus toxin in motor neurons. J Cell Sci 116, 4639-4650.
83. Jimenez JL, Smith GR, Contreras-Moreira B, Sgouros JG, Meunier FA, Bates PA and Schiavo G (2003) Functional recycling of C2 domains throughout evolution: a comparative study of synaptotagmin, protein kinase C and phospholipase C by sequence, structural and modelling approaches. J Mol Biol 333, 621-639.
84. Hafezparast M, Klocke R, Ruhrberg C, Marquardt A, Ahmad-Annuar A, Bowen S, Lalli G, Witherden AS, Hummerich H, Nicholson S, Morgan PJ, Oozageer R, Priestley JV, Averill S, King VR, Ball S, Peters J, Toda T, Yamamoto A, Hiraoka Y, Augustin M, Korthaus D, Wattler S, Wabnitz P, Dickneite C, Lampel S, Boehme F, Peraus G, Popp A, Rudelius M, Schlegel J, Fuchs H, Hrabe de Angelis M, Schiavo G, Shima DT, Russ AP, Stumm G, Martin JE and Fisher EMC (2003) Mutations in dynein link motor neuron degeneration to defects in retrograde transport. Science, 300, 808-812.
85. Caccin P, Rossetto O, Rigoni M, Johnson E, Schiavo G and Montecucco C (2003) VAMP/synaptobrevin cleavage by tetanus and botulinum neurotoxins is strongly enhanced by acidic liposomes. FEBS Lett 542, 132-136.
86. Meunier FA, Feng ZP, Molgó J, Zamponi GW and Schiavo G (2002) Glycerotoxin from Glycera convoluta stimulates neurosecretion by up-regulating N-type Ca2+ channel activity. Embo J 21, 6733-6743.
87. Herreros J and Schiavo G (2002) Lipid microdomains are involved in neurospecific binding and internalisation of clostridial neurotoxins. Int J Med Microbiol 291, 447-453.
88. Lalli G and Schiavo G (2002) Analysis of retrograde transport in motor neurons reveals common endocytic carriers for tetanus toxin and neurotrophin receptor p75NTR. J Cell Biol 156, 233-239.
89. Hawkes NA, Otero G, Winkler GS, Marshall N, Dahmus ME, Krappmann D, Scheidereit C, Thomas CL, Schiavo G, Erdjument-Bromage H, Tempst P and Svejstrup JQ (2002) Purification and characterization of the human elongator complex. J Biol Chem 277, 3047-3052.
90. Herreros J, Ng T and Schiavo G (2001) Lipid rafts act as specialized domains for tetanus toxin binding and internalization into neurons. Mol Biol Cell 12, 2947-2960.
91. Coppola T, Magnin-Luthi S, Perret-Menoud V, Gattesco S, Schiavo G and Regazzi R (2001) Direct interaction of the Rab3 effector RIM with Ca2+ channels, SNAP-25, and synaptotagmin. J Biol Chem 276, 32756-32762.
92. Kittler JT, Rostaing P, Schiavo G, Fritschy JM, Olsen R, Triller A and Moss SJ (2001) The subcellular distribution of GABARAP and its ability to interact with NSF suggest a role for this protein in the intracellular transport of GABA(A) receptors. Mol Cell Neurosci 18, 13-25.
93. Osborne SL, Thomas CL, Gschmeissner S and Schiavo G (2001) Nuclear PtdIns(4,5)P2 assembles in a mitotically regulated particle involved in pre-mRNA splicing. J Cell Sci, 114, 2501-2511.
94. Iglesias T, Cabrera-Poch N, Mitchell MP, Naven TJ, Rozengurt E and Schiavo G (2000) Identification and cloning of Kidins220, a novel neuronal substrate of protein kinase D. J Biol Chem 275, 40048-40056.
95. Sinha K, Box M, Lalli G, Schiavo G, Schneider H, Groves M, Siligardi G and Fairweather N (2000) Analysis of mutants of tetanus toxin Hc fragment: ganglioside binding, cell binding and retrograde axonal transport properties. Mol Microbiol 37, 1041-1051.
96. Herreros J, Lalli G and Schiavo G (2000) C-terminal half of tetanus toxin fragment C is sufficient for neuronal binding and interaction with a putative protein receptor. Biochem J 347, 199-204.
97. Herreros J, Lalli G, Montecucco C and Schiavo G (2000) Tetanus toxin fragment C binds to a protein present in neuronal cell lines and motoneurons. J Neurochem 74, 1941-1950.
98. Muller JM, Rabouille C, Newman R, Shorter J, Freemont P, Schiavo G, Warren G and Shima DT. (1999) An NSF function distinct from ATPase-dependent SNARE disassembly is essential for Golgi membrane fusion. Nat Cell Biol, 1, 335-340.
99. Lalli G, Herreros J, Osborne SL, Montecucco C, Rossetto O and Schiavo G (1999) Functional characterisation of tetanus and botulinum neurotoxins binding domains. J Cell Sci 112, 2715-2724.
100. Thomas CL, Steel J, Prestwich GD and Schiavo G (1999) Generation of phosphatidylinositol-specific antibodies and their characterization. Biochem Soc Trans 27, 648-652.
101. Osborne SL, Herreros J, Bastiaens PI and Schiavo (1999) Calcium-dependent oligomerization of synaptotagmins I and II. Synaptotagmins I and II are localized on the same synaptic vesicle and heterodimerize in the presence of calcium. J Biol Chem 274, 59-66.
102. Stamnes M, Schiavo G, Stenbeck G, Sollner TH and Rothman JE (1998) ADP-ribosylation factor and phosphatidic acid levels in Golgi membranes during budding of coatomer-coated vesicles. Proc Natl Acad Sci U S A 95, 13676-13680.
103. Tonello F, Schiavo G and Montecucco C (1997) Metal substitution of tetanus neurotoxin. Biochem J 322, 507-510.
104. Schiavo G, Stenbeck G, Rothman JE and Sollner TH (1997) Binding of the synaptic vesicle v-SNARE, synaptotagmin, to the plasma membrane t-SNARE, SNAP-25, can explain docked vesicles at neurotoxin-treated synapses. Proc Natl Acad Sci U S A 94, 997-100.
105. Schiavo G, Gu QM, Prestwich GD, Sollner TH and Rothman JE (1996) Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagmin. Proc Natl Acad Sci U S A 93, 13327-13332.
106. Matteoli M, Verderio C, Rossetto O, Lezzi N, Coco S, Schiavo G and Montecucco C (1996) Synaptic vesicle endocytosis mediates the entry of tetanus neurotoxin into hippocampal neurons. Proc Natl Acad Sci U S A 93, 13310-13315.
107. Osen-Sand A, Staple JK, Naldi E, Schiavo G, Rossetto O, Petitpierre S, Malgaroli A, Montecucco C and Catsicas S (1996) Common and distinct fusion proteins in axonal growth and transmitter release. J Comp Neurol 367, 222-234.
108. Morante S, Furenlid L, Schiavo G, Tonello F, Zwilling R and Montecucco C (1996) X-ray absorption spectroscopy study of zinc coordination in tetanus neurotoxin, astacin, alkaline protease and thermolysin. Eur J Biochem 235, 606-612.
109. Rossetto O, Gorza L, Schiavo G, Schiavo N, Scheller RH and Montecucco C (1996) VAMP/synaptobrevin isoforms 1 and 2 are widely and differentially expressed in nonneuronal tissues. J Cell Biol 132, 167-179.
110. Schiavo G, Gmachl MJ, Stenbeck G, Sollner TH and Rothman JE (1995) A possible docking and fusion particle for synaptic transmission. Nature 378, 733-736.
111. Schiavo G and Montecucco C (1995) Tetanus and botulism neurotoxins: isolation and assay. Methods Enzymol 248, 643-652.
112. Nielander HB, Onofri F, Valtorta F, Schiavo G, Montecucco C, Greengard P and Benfenati F (1995) Phosphorylation of VAMP/synaptobrevin in synaptic vesicles by endogenous protein kinases. J Neurochem 65, 1712-1720.
113. De Filippis V, Vangelista L, Schiavo G, Tonello F and Montecucco C (1995) Structural studies on the zinc-endopeptidase light chain of tetanus neurotoxin. Eur J Biochem 229, 61-69.
114. Schiavo G, Shone CC, Bennett MK, Scheller RH and Montecucco C. (1995) Botulinum neurotoxin type C cleaves a single Lys-Ala bond within the carboxyl-terminal region of syntaxins. J Biol Chem 270, 10566-10570.
115. Washbourne P, Schiavo G and Montecucco C (1995) Vesicle-associated membrane protein-2 (synaptobrevin-2) forms a complex with synaptophysin. Biochem J 305, 721-724.
116. Kochi SK, Schiavo G, Mock M and Montecucco C (1994) Zinc content of the Bacillus anthracis lethal factor. FEMS Microbiol Lett 124, 343-348.
117. Rossetto O, Schiavo G, Montecucco C, Poulain B, Deloye F, Lozzi L and Shone CC (1994) SNARE motif and neurotoxins. Nature 372, 415-416.
118. Schiavo G, Malizio C, Trimble WS, Polverino de Laureto P, Milan G, Sugiyama H, Johnson EA and Montecucco C (1994) Botulinum G neurotoxin cleaves VAMP/synaptobrevin at a single Ala-Ala peptide bond. J Biol Chem 269, 20213-20216.
119. Kochi SK, Martin I, Schiavo G, Mock M and Cabiaux V (1994) The effects of pH on the interaction of anthrax toxin lethal and edema factors with phospholipid vesicles. Biochemistry 33, 2604-2609.
120. de Paiva A, Ashton AC, Foran P, Schiavo G, Montecucco C and Dolly JO (1993) Botulinum A like type B and tetanus toxins fulfils criteria for being a zinc-dependent protease. J Neurochem 61, 2338-2341.
121. Schiavo G, Santucci A, Dasgupta BR, Mehta PP, Jontes J, Benfenati F, Wilson MC and Montecucco C (1993) Botulinum neurotoxins serotypes A and E cleave SNAP-25 at distinct COOH-terminal peptide bonds. FEBS Lett 335, 99-103.
122. Schiavo G, Rossetto O, Catsicas S, Polverino de Laureto P, DasGupta BR, Benfenati F and Montecucco C (1993) Identification of the nerve terminal targets of botulinum neurotoxin serotypes A, D, and E. J Biol Chem 268, 23784-23787.
123. Onaderra M, Mancheno JM, Gasset M, Lacadena J, Schiavo G, Martinez del Pozo A and Gavilanes JG (1993) Translocation of -sarcin across the lipid bilayer of asolectin vesicles. Biochem J 295, 221-225.
124. Poulain B, Rossetto O, Deloye F, Schiavo G, Tauc L and Montecucco C (1993) Antibodies against rat brain vesicle-associated membrane protein (synaptobrevin) prevent inhibition of acetylcholine release by tetanus toxin or botulinum neurotoxin type B. J Neurochem 61, 1175-1178.
125. Patarnello T, Bargelloni L, Rossetto O, Schiavo G and Montecucco C (1993) Neurotransmission and secretion. Nature 364, 581-582.
126. Schiavo G, Shone CC, Rossetto O, Alexander FC and Montecucco C (1993) Botulinum neurotoxin serotype F is a zinc endopeptidase specific for VAMP/synaptobrevin. J Biol Chem 268, 11516-11519.
127. Schiavo G, Rossetto O, Santucci A, DasGupta BR and Montecucco C (1992) Botulinum neurotoxins are zinc proteins. J Biol Chem 267, 23479-23483.
128. Schiavo G, Benfenati F, Poulain B, Rossetto O, Polverino de Laureto P, DasGupta BR and Montecucco C (1992) Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin. Nature 359, 832-835.
129. Schiavo G, Poulain B, Rossetto O, Benfenati F, Tauc L and Montecucco C (1992) Tetanus toxin is a zinc protein and its inhibition of neurotransmitter release and protease activity depend on zinc. EMBO J 11, 3577-3583.
130. Calappi E, Masserini M, Schiavo G, Montecucco C and Tettamanti G (1992) Lipid interaction of tetanus neurotoxin. A calorimetric and fluorescence spectroscopy study. FEBS Lett 309, 107-110.
131. Rossetto O, Schiavo G, Polverino de Laureto P, Fabbiani S and Montecucco C (1992) Surface topography of histidine residues of tetanus toxin probed by immobilized-metal-ion affinity chromatography. Biochem J 285, 9-12.
132. Amadori A, De Silvestro G, Zamarchi R, Veronese ML, Mazza MR, Schiavo G, Panozzo M, De Rossi A, Ometto L, Mous J, Barelli A, Borri A, Salmaso L and Chieco-Bianchi L (1992) CD4 epitope masking by gp120/anti-gp120 antibody complexes. A potential mechanism for CD4+ cell function down-regulation in AIDS patients. J Immunol 148, 2709-2716.
133. Schiavo G, Ferrari G, Rossetto O and Montecucco C (1991) Tetanus toxin receptor. Specific cross-linking of tetanus toxin to a protein of NGF-differentiated PC 12 cells. FEBS Lett 290, 227-230.
134. Massari S, Folena E, Ambrosin V, Schiavo G and Colonna R (1991) pH-dependent lipid packing, membrane permeability and fusion in phosphatidylcholine vesicles. Biochim Biophys Acta 1067, 131-138.
135. Gasset M, Onaderra M, Martinez del Pozo A, Schiavo G, Laynez J, Usobiaga P and Gavilanes JG (1991) Effect of the antitumour protein alpha-sarcin on the thermotropic behaviour of acid phospholipid vesicles. Biochim Biophys Acta 1068, 9-16.
136. Schiavo G, Demel R and Montecucco C (1991) On the role of polysialoglycosphingolipids as tetanus toxin receptors. A study with lipid monolayers. Eur J Biochem 199, 705-711.
137. Demel R, Schiavo G, de Kruijff B and Montecucco C (1991) Lipid interaction of diphtheria toxin and mutants. A study with phospholipid and protein monolayers. Eur J Biochem 197, 481-486. 
138. Papini E, Santucci A, Schiavo G, Domenighini M, Neri P, Rappuoli R and Montecucco C (1991) Tyrosine-65 is photolabelled by 8-azidoadenine and 8-azidoadenosine at the NAD+ binding site of diphtheria toxin. J Biol Chem 266, 2494-2498.
139. Schiavo G, Papini E, Genna G and Montecucco C (1990) An intact interchain disulfide bond is required for the neurotoxicity of tetanus toxin. Infect Immun 58, 4136-4141.
140. Schiavo G, Boquet P, Dasgupta BR and Montecucco C (1990) Membrane interactions of tetanus and botulinum neurotoxins: a photolabelling study with photoactivatable phospholipids. J Physiol (Paris) 84, 180-187.
141. Singh BR, Fuller MP and Schiavo G (1990) Molecular structure of tetanus neurotoxin as revealed by Fourier transform infrared and circular dichroic spectroscopy. Biophys Chem 36, 155-166.
142. Dabbeni-Sala F, Schiavo G and Palatini P (1990) Mechanism of local anesthetic effect on mitochondrial ATP synthase as deduced from photolabelling and inhibition studies with phenothiazine derivatives. Biochim Biophys Acta 1026, 117-125.
143. Papini E, Schiavo G, Rappuoli R and Montecucco C (1990) Histidine-21 is involved in diphtheria toxin NAD+ binding. Toxicon 28, 631-635. 
144. Capaldi RA, Zhang YZ, Rizzuto R, Sandona D, Schiavo G and Bisson R (1990) The two oxygen-regulated subunits of cytochrome c oxidase in Dictyostelium discoideum derive from a common ancestor. FEBS Lett 261, 158-160.
145. Papini E, Schiavo G, Sandona D, Rappuoli R and Montecucco C (1989) Histidine 21 is at the NAD+ binding site of diphtheria toxin. J Biol Chem 264, 12385-12388.
146. Schiavo G and Bisson R (1989) Oxygen influences the subunit structure of cytochrome c oxidase in the slime mold Dictyostelium discoideum. J Biol Chem 264, 7129-7134.
147. Montecucco C, Schiavo G and Dasgupta BR (1989) Effect of pH on the interaction of botulinum neurotoxins A, B and E with liposomes. Biochem J 259, 47-53.
148. Sonnino S, Acquotti D, Chigorno V, Pitto M, Montecucco C, Schiavo G, Kirschner G and Tettamanti G (1988) Recent advances in the chemistry and technology of gangliosides. Indian J Biochem Biophys 25, 144-149.
149. Montecucco C, Schiavo G, Gao Z, Bauerlein E, Boquet P and DasGupta BR (1988) Interaction of botulinum and tetanus toxins with the lipid bilayer surface. Biochem J 251, 379-383.
150. Moscufo N, Gallina A, Schiavo G, Montecucco C and Tomasi M (1987) Multiple lipid interactions of the Sendai virus fusogenic protein. J Biol Chem 262, 11490-11496.
151. Papini E, Schiavo G, Tomasi M, Colombatti M, Rappuoli R and Montecucco C (1987) Lipid interaction of diphtheria toxin and mutants with altered fragment B. 2. Hydrophobic photolabelling and cell intoxication. Eur J Biochem 169, 637-644.
152. Montecucco C, Schiavo G, Bacci B and Bisson R (1987) Isolation and characterization of cytochrome c oxidase from bird and fish heart mitochondria. Comp Biochem Physiol B 87, 851-856.
153. Bisson R, Schiavo G and Montecucco C (1987) ATP induces conformational changes in mitochondrial cytochrome c oxidase. Effect on the cytochrome c binding site. J Biol Chem 262, 5992-5998.
154. Papini E, Colonna R, Schiavo G, Cusinato F, Tomasi M, Rappuoli R and Montecucco C (1987) Diphtheria toxin and its mutant crm197 differ in their interaction with lipids. FEBS Lett 215, 73-78.
155. Bisson R and Schiavo G (1986) Two different forms of cytochrome c oxidase can be purified from the slime mold Dictyostelium discoideum. J Biol Chem 261, 4373-4376.
156. Degli Esposti M, Avitabile E, Barilli M, Schiavo G, Montecucco C and Lenaz G (1986) Comparative biochemistry of the ubiquinol-cytochrome c oxidoreductase (EC isolated from different heart mitochondria. Comp Biochem Physiol B 85, 543-552.
157. Montecucco C, Tomasi M, Schiavo G and Rappuoli R (1986) Hydrophobic photolabelling of pertussis toxin subunits interacting with lipids. FEBS Lett 194, 301-304.
158. Montecucco C, Schiavo G, Brunner J, Duflot E, Boquet P and Roa M (1986) Tetanus toxin is labelled with photoactivatable phospholipids at low pH. Biochemistry 25, 919-924.
159. Montecucco C and Schiavo G (1986) 1-Palmitoyl-2-(p-benzoyl)benzoyl phosphatidylcholine, a photoactive phospholipid for the labelling of membrane components. Biochem J 237, 309-312.
160. Montecucco C, Schiavo G and Bisson R (1986) ATP binding to bovine heart cytochrome c oxidase. A photoaffinity labelling study. Biochem J 234, 241-243.
161. Bisson R, Schiavo G and Papini E. (1985) Cytochrome c oxidase from the slime mold Dictyostelium discoideum: purification and characterization. Biochemistry, 24, 7845-7852.
162. Montecucco C, Schiavo G and Tomasi M (1985) pH-dependence of the phospholipid interaction of diphtheria-toxin fragments. Biochem J 231, 123-128.

Research Papers (as authors' consortium)
163. Creutz CE, Moss S, Edwardson JM, Hide I, Gomperts B and Participants of the EMBO Course "Advanced Techniques for Studying Secretion" (1992) Differential recognition of secretory vesicles by annexins. Biochem Biophys Res Commun 184, 347-52.

Reviews and Book Chapters
1.    Surana S, Villarroel-Campos D, Lazo OM, Moretto E, Tosolini AP, Rhymes ER, Richter S, Sleigh JN and Schiavo G (2019) The evolution of the axonal transport toolkit. Traffic, in press.
2. Sleigh JN, Rossor AM, Fellows AD, Tosolini AP and Schiavo G (2019) Axonal transport and neurological disease. Nat Rev Neurol, in press.
3. Villarroel-Campos D, Schiavo G and Lazo OM (2018) The many disguises of the signalling endosome. FEBS Lett, 592, 3615-3632.
4. Cesca F, Schiavo G and Benfenati F (2018) Kidins220/ARMS transgenic lines could be instrumental to the understanding of the molecular mechanisms leading to spastic paraplegia and obesity. Eur J Neurol 25, e107.
5. Terenzio M, Schiavo G and Fainzilber M (2017) Compartmentalized Signaling in Neurons: from Cell Biology to Neuroscience. Neuron 96, 667-679.
6. Surana S, Tosolini AP, Meyer IF, Fellows AD, Novoselov S and Schiavo G (2017) The travel diaries of tetanus and botulinum neuroxins. Toxicon, doi: 10.1016/j.toxicon.2017.10.008.
7. Sleigh JN, Vagnoni A, Twelvetrees AE and Schiavo G (2017) Methodological advances in imaging intravital axonal transport. F1000Res 6, 200.
8. Gibbs K, Greensmith L and Schiavo G (2015) Regulation of axonal transport by protein kinases. Trend Biochem Sci 40, 597-610.
9. Schmieg N, Bercsenyi K and Schiavo G (2015) Uptake and transport of clostridium neurotoxins. In "The comprehensive sourcebook of bacterial protein toxins." 4th Ed, JE Alouf, D Ladant and MR Popoff Eds, Elsevier, Oxford (UK) 337-360.
10. Debaisieux S and Schiavo G (2014) TiME for TMEM106B. EMBO J 33, 405-6.
11. Schmieg N, Menendez G, Schiavo G and Terenzio M (2014) Signalling endosomes in axonal transport: travel updates on the molecular highway. Sem Cell Biol 27, 32-43.
12. Cesca F, Schiavo G and Benfenati F (2013) Novel experimental models to study neurotrophin function. Eur J Neurodegen Dis 2, 89-99.
13. Schiavo G, Greensmith L, Hafezparast M and Fisher EMC (2013) Cytoplasmic dynein heavy chain: the servant of many masters. Trends Neurosci 36, 641-51.
14. Schiavo G and Fainzilber M (2013) Alternative energy for neuronal motors. Nature 495, 178-180.
15. Chancellor MB, Elovic E, Esquenazi A, Naumann M, Segal KR, Schiavo G, Smith CP and Ward AB (2013) Evidence-based review and assessment of botulinum neurotoxin for the treatment of urologic conditions. Toxicon 67, 129-40.
16. Naumann M, Dressler D, Hallett M, Jankovic J, Schiavo G, Segal KR, Truong D (2013) Evidence-based review and assessment of botulinum neurotoxin for the treatment of secretory disorders. Toxicon 67, 141-52.
17. Thige AP and Schiavo G (2013) Botulinum neurotoxins: mechanism of action. Toxicon 67, 87-93.
18. Bercsenyi K, Giribaldi F and Schiavo G (2013) The elusive compass of clostridial neurotoxins: deciding when and where to go. Curr Top Microbiol Immunol 364, 91-113.
19. Neubrand VE, Cesca F, Benfenati F and Schiavo G (2012) Kidins220/ARMS as functional mediator of multiple receptor signalling pathways. J Cell Sci 125, 1-10.
20. Kuta A, Hafezparast M, Schiavo G and Fisher EMC (2012) Genetic insights into mammalian cytoplasmic dynein function provided by novel mutations in mouse. In "Dyneins." S King Ed, Academic Press, London (UK) 483-504.
21. Salinas S, Schiavo G and Kremer EJ (2010) The hitchhiker's guide to the nervous system: axonal transport of neurotropic viruses and toxins. Nat Rev Microbiol 8, 645-55.
22. Terenzio M and Schiavo G (2010) The more, the better: the BICD family gets bigger. EMBO J 29, 1625-1626.
23. Warner TT, Schiavo G and Granata A (2010) TorsinA and DYT1 dystonia: a synaptopathy? Biochem Soc Trans 38, 452-456.
24. Granata A, Schiavo G and Warner TT (2009) TorsinA and Dystonia: from nuclear envelope to synapse. J Neurochem 109, 1596-1609.
25. Caleo M and Schiavo G (2009) Central effects of tetanus and botulinum neurotoxins. Toxicon 54, 593-599.
26. Bilsland LG and Schiavo G (2008) Axonal transport tracers. In "The New Encyclopedia of Neuroscience." LR Squire Ed, Academic Press, Oxford (UK) 1209-1216.
27. Tooze SA and Schiavo G (2008) Liaisons dangereuses: autophagy, neuronal survival and neurodegeneration. Curr Opin Neurobiol 18, 504-515.
28. Salinas S, Bilsland LG and Schiavo G (2008) Molecular landmarks along the axonal route: axonal transport in health and disease. Curr Opin Cell Biol 20, 445-453.
29. Salinas S, Carazo-Salas RE, Proukakis C, Schiavo G and Warner TT (2007) Spastin and microtubules: functions in health and disease. J Neurosci Res 85, 2778-2782.
30. Hammond GRV and Schiavo G (2007) The phosphoinositides: Under-PPIning synaptic function in health and disease. Dev Neurobiol 67, 1232-1247.
31. Schiavo G (2006) Dangerous liaisons on neurons. Nature, 444, 1019-1020.
32. Bohnert S, Deinhardt K, Salinas S and Schiavo G. (2006) Uptake and transport of clostridium neurotoxins. In "The comprehensive sourcebook of bacterial protein toxins." 3rd Ed, JE Alouf and MR Popoff Eds, Academic Press, London (UK) 390-408.
33. Montecucco C, Schiavo G and Pantano S (2005) SNARE complexes and neuroexocytosis: how many, how close? Trends Biol Sci 30, 367-372.
34. Deinhardt K and Schiavo G (2005) Endocytosis and retrograde axonal traffic in motor neurons. Biochem Soc Trans 72, 139-150.
35. Montecucco C, Rossetto O and Schiavo G (2004) Presynaptic receptor arrays for clostridial neurotoxins. Trends Microbiol 12, 442-446.
36. Schiavo G and Chao MV (2004) Motors, adaptors, and receptors: Key elements of neuronal transport. J Neurobiol 58, 161-163.
37. Hammond G, Thomas CL and Schiavo G (2004) Nuclear phosphoinositides and their functions. Curr Top Microbiol Immunol 282, 177-206.
38. Lalli G, Bohnert S, Verastegui C and Schiavo G (2003) The journey of tetanus and botulinum neurotoxins in neurons. Trends Microbiol 11, 431-437.
39. Verastegui C, Lalli G, Bohnert S, Meunier FA and Schiavo G (2002) Clostridial neurotoxin. J Toxicol: Toxin Rev 21, 203-227.
40. Lalli G, Herreros J and Schiavo G. (2002) Neurospecific binding and trafficking of tetanus toxin. In "Scientific and Therapeutic Aspects of Botulinum Toxin" M Brin, M Hallett and J Jankovic Eds, Lippincott, Williams & Wilkins, New York (NY) 49-59.
41. Meunier FA, Schiavo G and Molgo J (2002) Botulinum neurotoxins: from paralysis to recovery of functional neuromuscular transmission. J Physiol (Paris) 96, 105-113.
42. Meunier FA, Herreros J, Schiavo G, Poulain B and Molgo J. (2002) Molecular mechanism of action of botulinal neurotoxins and the synaptic remodeling they induce in vivo at the skeletal neuromuscular junction. In "Neurotoxicology Handbook Vol. I" EJ Massaro Ed, Humana Press, Totowa (NJ) 305-347.
43. Rossetto O, Schiavo G and Montecucco C. (2001) Clostridium tetani. In "Molecular Medical Microbiology" M Sussman Ed, Academic Press, London (UK) 1905-1919.
44. Osborne SL, Meunier FA and Schiavo G (2001) Phosphoinositides as key regulators of synaptic function. Neuron 32, 9-12.
45. Schiavo G and Van Der Goot FG (2001) The Bacterial Toxin Toolkit. Nat Rev Mol Cell Biol 2, 530-538.
46. Rossetto O, Seveso M. Caccin P, Schiavo G and Montecucco C (2001) Tetanus and botulinum neurotoxins: turning bad guys into good by research. Toxicon 39, 27-41.
47. Schiavo G, Matteoli M and Montecucco C (2000) Neurotoxins and neuroexocytosis. Physiol Rev 80, 717-766.
48. Rossetto O, De Bernard M, Pellizzari R, Vitale G, Schiavo G and Montecucco C (2000) Bacterial toxins with intracellular protease activity. Clin Chim Acta 291, 189-199.
49. Schiavo G and Montecucco C (2000) Tossine batteriche. In "Tossicologia Molecolare e cellulare" Cantelli Forti G, Galli CL, Hrelia P and Marinovich M Eds, UTET, Torino (I) 149-159.
50. Owen DJ and Schiavo G (1999) A handle on NSF. Nat Cell Biol 1, E127-E128.
51. O'Kane CJ, Schiavo G and Sweeney ST (1999) Toxins that affect neurotransmitter release. In "Neurotransmitter release" H Bellen Ed, Oxford University Press, Oxford (UK) 208-236.
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Edited Monographies
99. Albanese A, Cardoso F, Fujinaga Y, Jankovic J, Rummel A and Schiavo G (2018) Toxins 2017 conference in Madrid. Toxicon 147, 1.
100. Albanese A, Bigalke H, Foster K, Hallett M, Jankovic J, Montecucco C and Schiavo G (2009) Toxins 2008: Basic and Therapeutic Aspects of Botulinum and Tetanus Toxins. Toxicon 54, Issue 5.
101. Schiavo G and Chao MV Eds (2004) Axonal transport. J Neurobiol 58, Issue 2.



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